Overview
Lys-D-Pro-Val is a synthetic tripeptide consisting of lysine (Lys), D-proline (D-Pro), and valine (Val). It is commonly used in biochemical and pharmaceutical research due to its unique structural configuration, which includes a D-amino acid (D-Pro). This peptide is often employed as a reference standard or building block in peptide synthesis. Its applications extend to drug development, where it may serve as a model compound for studying peptide interactions or as a precursor for more complex molecules. The presence of D-proline enhances its stability against enzymatic degradation, making it valuable for certain research applications.
Physical and Chemical Properties
Lys-D-Pro-Val appears as a white to off-white powder with a molecular weight of approximately 398.5 g/mol. It is soluble in water and polar organic solvents, which facilitates its use in laboratory settings. The peptide's stability is maintained under recommended storage conditions, typically at -20°C in a dry environment. Key properties include high purity and resistance to enzymatic breakdown due to the inclusion of D-proline. These characteristics make it suitable for precise experimental work, particularly in studies requiring stable peptide structures. However, its exact melting and boiling points are not widely documented.
Main Applications
Lys-D-Pro-Val is primarily utilized in pharmaceutical research and peptide synthesis. Its unique structure, featuring D-proline, makes it a valuable tool for studying peptide stability and interactions. Researchers often use it as a reference standard in analytical chemistry to validate methods or calibrate instruments. In drug development, this peptide may serve as a scaffold for designing novel therapeutic agents. Its resistance to enzymatic degradation is particularly advantageous for in vitro and in vivo studies. Additionally, it finds use in biochemical assays where precise peptide sequences are required.
Safety and Storage
Proper handling of Lys-D-Pro-Val is essential to ensure safety and maintain its integrity. It should be stored at -20°C in a dry, airtight container to prevent degradation. Exposure to moisture or elevated temperatures can compromise its stability. Safety precautions include wearing gloves, protective eyewear, and lab coats to avoid skin or eye contact. Inhalation or ingestion should be avoided, and the peptide should be used in a well-ventilated area. In case of accidental exposure, rinse thoroughly with water and seek medical advice if necessary.
B2B Procurement Guide
When procuring Lys-D-Pro-Val, it is crucial to verify the peptide's purity and specifications with the supplier. Reputable suppliers typically provide certificates of analysis (CoA) detailing the product's characteristics. Buyers should also confirm storage and shipping conditions to ensure the peptide arrives in optimal condition. Price ranges vary depending on quantity and supplier, so obtaining multiple quotes is advisable. Bulk purchases may offer cost savings, but storage capacity should be considered. For research purposes, small quantities with high purity are often preferred to minimize waste and ensure experimental accuracy.
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