Lithium Titanate
Overview
2-Amino-5-chlorobenzophenone (CAS 50767-79-8) is an organic compound primarily utilized as a building block in pharmaceutical and agrochemical synthesis. Its molecular structure combines a benzophenone backbone with amino and chloro functional groups, enabling reactivity in various chemical transformations. The compound is synthesized through controlled chlorination and amination processes, ensuring high purity for industrial applications. As a specialty intermediate, it plays a critical role in producing active pharmaceutical ingredients (APIs) and crop protection agents. Manufacturers typically supply it in powder form with purity levels exceeding 98%, meeting stringent industry standards for consistency and performance.
Physical and Chemical Properties
This compound presents as a light yellow to beige crystalline solid with a melting point range of 120-125°C. Its molecular weight of 231.68 g/mol reflects a balanced structure suitable for further derivatization. The presence of both amino and chloro groups enhances its solubility in polar organic solvents like ethanol and acetone, while water solubility remains limited. Key chemical properties include stability under normal storage conditions and reactivity as an electrophile in substitution reactions. Its aromatic system contributes to UV absorption, necessitating protection from prolonged light exposure during handling. Analytical methods such as HPLC and NMR are commonly employed to verify purity and structural integrity.
Main Applications
2-Amino-5-chlorobenzophenone serves as a versatile intermediate in pharmaceutical manufacturing, particularly in synthesizing benzodiazepine analogs and other nitrogen-containing heterocycles. Its structural motifs are valuable for constructing molecules with biological activity, including anxiolytics and anticonvulsants. In agrochemicals, the compound contributes to the development of herbicides and fungicides, where the chloro-substituted aromatic ring enhances target specificity. Additionally, it finds niche applications in dye synthesis and material science research, leveraging its electron-rich aromatic system for specialized reactions.
Safety and Storage
Handling requires precautions due to potential skin and eye irritation. Personal protective equipment (PPE) such as nitrile gloves and safety goggles is mandatory. Avoid dust formation and ensure local exhaust ventilation in work areas to minimize inhalation risks. Storage should occur in tightly sealed containers under cool, dry conditions, separated from strong oxidizers and acids. Shelf life typically exceeds two years when stored properly. Spills should be contained with inert absorbents and disposed of as hazardous waste in compliance with local regulations.
B2B Procurement Guide
When sourcing 2-Amino-5-chlorobenzophenone, prioritize suppliers with documented quality control processes and certifications like ISO 9001. Request certificates of analysis (CoA) specifying purity (≥98%), residual solvents, and heavy metal content. Bulk procurement (25kg drums) often reduces unit costs, but validate storage capacity beforehand. Logistics considerations include temperature-controlled transport for sensitive batches and Incoterms clarity (e.g., FOB, CIF). Negotiate lead times proactively, as custom synthesis may require 4-8 weeks. For R&D-scale purchases, opt for suppliers offering small-quantity packaging (100g-1kg) with batch traceability.
Related Manufacturers
- 主营：二羟基吲哚啉氢溴酸、半叶素、石胆酸钠盐、6-二羟基吲哚、苯基周位酸:8-苯胺、2-辛基十二醇、2-巯基噻唑啉、2-巯基苯并咪唑、L-丙交酯、7-去氢胆固醇、1-氨基环丙烷羧酸、4-联苯甲醇丙烯酸酯、4-羟乙烯基氧基二苯、D(+)-丙交酯、熊去氧胆酸钠盐、水解角蛋白、乙烯利、环丙磺酰胺、苄氧基胺盐酸盐、咪鲜胺、可比落、乙交酯、环巴胺、丙基丙二酸二甲酯、腺苷
- 主营：三甲基戊二醇、三甲基戊二醇二苯甲酸、羟基乙酸、N-二羟乙基对甲苯胺、N-二异丙醇对甲苯胺、柠檬酸铝、间二三氟甲苯、双酚F
- 主营：肌氨酸钠、硫化锰、V50偶氮二异丁脒盐酸盐、PX-4MP、腰果酚缩水甘油醚、乙硫氮、二新癸酸二甲基锡、三硫代碳酸钠、芥酸PKO、四氧化三锰
- 主营：甘氨酸、甘氨酰、苯硫醚、50767、阻燃剂、月桂胺、酸性橙、去铁酮、豆油酸、二苯胺、西瓜酮、八乙基、硫酸锆、磺化钯、二氰基、硫酸锶、硫酸锰、二苯胍、铝酸锶、聚合物、肌氨酸、四氢萘、磷酸铵、甲乙基、甲基亚、碳酸镁
- 主营：吩嗪、肌氨酸钠、偶氮二异丁脒盐酸盐、1-苯基-5-巯基四氮唑、V50、H酸、DDS、甲基磺酸铋、二恶唑啉、柠檬酸铋、赛克、双氟代碳酸乙烯酯