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Licochalcone B

Updated: 2026-08-15

Overview

Licochalcone B is a natural flavonoid compound extracted from the roots of licorice plants (Glycyrrhiza species). It belongs to the chalcone subclass, characterized by its distinct yellow color and bioactive properties. This compound has garnered attention in both academic and industrial circles due to its potential therapeutic benefits, including antioxidant and anti-inflammatory effects. In B2B markets, licochalcone B is typically supplied as a high-purity powder for use in pharmaceutical formulations, cosmetic products, and nutraceuticals. Its growing popularity stems from its natural origin and multifunctional properties, making it a sought-after ingredient in health and wellness applications.

Physical and Chemical Properties

【麦德生】甘草查尔酮B 58749-23-8 分析标准品 HPLC≥98% 现货成都麦德生科技有限公司

Licochalcone B appears as a yellow crystalline powder with a molecular weight of 270.28 g/mol. Its molecular formula is C16H14O4, and it has a melting point of approximately 160-162°C. The compound is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) but exhibits poor solubility in water. Key chemical properties include its ability to act as a free radical scavenger, contributing to its antioxidant effects. The presence of phenolic hydroxyl groups in its structure enhances its reactivity and biological activity. These properties make it a valuable component in formulations requiring stability and efficacy.

Main Applications

Licochalcone B is primarily used in the pharmaceutical industry for its potential anti-inflammatory and antimicrobial properties. Research suggests it may help in managing conditions like acne, dermatitis, and other skin disorders. Additionally, it is explored for its role in cancer prevention due to its antioxidant capabilities. In the cosmetics industry, licochalcone B is incorporated into skincare products for its ability to soothe irritated skin and reduce oxidative stress. It is also used in dietary supplements aimed at promoting overall health and wellness. Its versatility and natural origin make it a preferred choice for formulators seeking bioactive ingredients.

Safety and Storage

【麦德生】去氧土大黄苷 30197-14-9 分析标准品 HPLC≥98% 现货成都麦德生科技有限公司

While licochalcone B is generally considered safe for use in regulated applications, proper handling is essential to avoid potential hazards. Direct contact with skin or eyes should be avoided, and protective equipment such as gloves and goggles is recommended during handling. Storage conditions are critical to maintaining the compound's stability. It should be kept in a cool, dry environment, protected from light and moisture. Properly sealed containers are necessary to prevent degradation and ensure longevity. Suppliers often provide material safety data sheets (MSDS) for detailed safety guidelines.

B2B Procurement Guide

When procuring licochalcone B, buyers should prioritize purity and supplier reliability. High-performance liquid chromatography (HPLC) analysis should confirm a purity level of ≥98%. Certificates of analysis (CoA) and Good Manufacturing Practice (GMP) certifications are indicators of a reputable supplier. Price variations are common based on purity, quantity, and supplier location. Bulk purchases may offer cost advantages, but consistency in batch quality is paramount. Buyers are advised to request samples for testing before committing to large orders to ensure the product meets their specific requirements.

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