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Lactobionic Acid

Updated: 2026-07-24

Overview

Lactobionic acid reagent, chemically known as 4-O-β-D-Galactopyranosyl-D-gluconic acid, is a derivative of lactose oxidation. It is widely recognized for its chelating and antioxidant properties, making it valuable in various industries. The compound is particularly noted for its role in pharmaceuticals and cosmetics, where it serves as a humectant and stabilizer. In biochemical research, lactobionic acid is used to study oxidative stress and cellular processes. Its ability to chelate metal ions also makes it useful in medical applications, such as reducing iron overload in patients with hemochromatosis. The reagent is typically supplied as a white crystalline powder, ensuring ease of handling and storage.

Physical and Chemical Properties

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Lactobionic acid reagent is a white to off-white crystalline powder with a molecular weight of 358.30 g/mol. It is highly soluble in water, which facilitates its use in aqueous solutions, and slightly soluble in ethanol. The compound has a melting point range of 120-125°C, though its boiling point is not well-documented due to decomposition at higher temperatures. Key chemical properties include its chelating ability, which allows it to bind metal ions effectively. This property is leveraged in medical and cosmetic formulations to prevent oxidative damage. Additionally, lactobionic acid acts as a humectant, retaining moisture in skincare products. Its stability under normal storage conditions makes it a reliable choice for industrial applications.

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Main Applications

Lactobionic acid reagent is predominantly used in the pharmaceutical industry, where it serves as an active ingredient in treatments for iron overload disorders. Its chelating properties help remove excess iron from the body, reducing toxicity. The compound is also employed in cosmetic formulations, particularly in anti-aging products, due to its antioxidant and moisturizing effects. In the food industry, lactobionic acid is used as a preservative and stabilizer, extending the shelf life of products. Its mild acidity and compatibility with other ingredients make it a versatile additive. Research applications include its use as a model compound for studying glycobiology and oxidative stress mechanisms.

Safety and Storage

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Proper handling of lactobionic acid reagent is essential to ensure safety. The compound should be stored in a cool, dry environment, away from direct sunlight and moisture. Containers must be tightly sealed to prevent contamination and degradation. Although it is not highly toxic, protective equipment such as gloves and goggles should be worn to avoid skin or eye contact. In case of accidental exposure, rinse the affected area with plenty of water and seek medical advice if irritation persists. Disposal should comply with local regulations for chemical waste. Suppliers often provide safety data sheets (SDS) with detailed handling instructions, which should be reviewed before use.

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B2B Procurement Guide

When procuring lactobionic acid reagent, buyers should prioritize suppliers with a proven track record of quality and reliability. Key factors to consider include the purity of the compound, typically ranging from 98% to 99%, and verification of the CAS number (96-82-2) to ensure authenticity. Bulk purchases may offer cost advantages, but storage capacity and shelf life should be evaluated to avoid waste. Requesting samples for testing can help verify compatibility with specific applications. Additionally, inquire about the supplier's logistics capabilities to ensure timely delivery and proper packaging to prevent damage during transit.

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