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L-Cysteine, anhydrous

Updated: 2026-07-24

Overview

Anhydrous cysteine is the free-base form of the amino acid cysteine, lacking water molecules in its crystalline structure. It plays critical roles in protein synthesis and antioxidant mechanisms. As a building block for glutathione, it contributes to cellular detoxification. The anhydrous form is preferred in industrial applications due to its stability and higher active compound concentration compared to hydrated variants.

Physical and Chemical Properties

This compound exhibits characteristic thiol (-SH) group reactivity, participating in redox reactions and disulfide bond formation. Its sulfur content enables metal chelation properties. The crystalline powder has low volatility but may emit sulfur dioxide when heated to decomposition. pH-dependent solubility makes it versatile for formulation across acidic to neutral conditions in end products.

Main Applications

In pharmaceuticals, it serves as a mucolytic agent in cough syrups and as a precursor for N-acetylcysteine production. The food industry utilizes it as dough conditioner (E920) and flavor enhancer. Cosmetic formulations leverage its antioxidant properties in skin care products and hair straightening treatments. Research applications include cell culture media supplementation and biochemical studies of thiol-disulfide interchange reactions.

Safety and Storage

Proper storage requires airtight containers with desiccants to prevent moisture absorption and oxidation. Shelf life typically exceeds 2 years when stored below 25°C. Handling precautions include using nitrile gloves and dust masks to prevent respiratory or dermal irritation. Spills should be cleaned immediately with damp cloths to minimize dust dispersion in work areas.

B2B Procurement Guide

Industrial buyers should prioritize suppliers with pharmaceutical-grade (USP/EP) certification for critical applications. Bulk shipments typically use 25kg fiber drums with polyethylene liners. Key quality indicators include low heavy metal content (<10ppm) and microbiological specifications. Request certificates of analysis for each batch, verifying HPLC purity and residual solvent levels where applicable.

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