Overview
Kathon CG is a synergistic blend of methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI), developed by Rohm and Haas (now Dow Chemical). As a highly effective preservative, it inhibits bacteria, yeasts, and molds in aqueous systems. Its commercial formulation typically contains 1.5% active ingredients in a magnesium chloride and nitrate solution. The compound gained prominence in the 1980s as a replacement for formaldehyde-releasing preservatives. Its efficacy at extremely low concentrations (often below 15 ppm) makes it cost-effective for manufacturers while maintaining product shelf life. However, its use requires careful formulation due to potential sensitization risks.
Physical and Chemical Properties
Kathon CG exhibits excellent thermal stability, remaining effective up to 40°C for long-term storage and brief exposures to 80°C during production. Its antimicrobial action derives from electrophilic attack on microbial thiol groups, disrupting metabolic pathways. The 3:1 ratio of MCI to MI provides broad-spectrum protection with reduced irritation potential compared to MI alone. In solution, it demonstrates good compatibility with most surfactants and emulsifiers used in personal care. However, reactivity may occur with strong nucleophiles (e.g., amines, thiols) or reducing agents. Formulators should conduct compatibility tests when combining with new ingredients.
Main Applications
In personal care, Kathon CG primarily preserves rinse-off products like shampoos (0.0015% max) and shower gels. Industrial applications include adhesives, paints, and metalworking fluids where microbial contamination risks exist. Its low use concentration minimizes formulation impact while providing 12-24 month preservation. The textile industry employs it as a slimicide in process waters. Unlike some preservatives, it doesn't contribute to VOC emissions. Recent innovations include encapsulated forms for delayed release in challenging formulations. Regulatory-approved concentrations vary by region, requiring manufacturers to adjust formulas for target markets.
Safety and Storage
Proper handling requires nitrile gloves and eye protection due to potential skin and eye irritation. The EU classifies it as skin sensitizer (Category 1B) with restricted concentrations in leave-on products (0.00075% max since 2016). Storage tanks should be constructed from 316 stainless steel or polyethylene. Avoid contact with carbon steel or copper alloys which may cause degradation. Shelf life typically reaches two years when stored below 25°C in original sealed containers. Users should monitor pH in formulations, as alkaline conditions (pH>9) accelerate decomposition.
B2B Procurement Guide
When sourcing Kathon CG, verify the supplier's Certificate of Analysis includes active ingredient assay (typically 14.0-15.4%), chloride content, and pH (2.0-5.0). Premium grades may offer lower impurity levels for sensitive applications. Bulk purchases (200kg drums) commonly attract 10-15% discounts versus retail packaging. For global shipments, confirm the product meets destination regulations - China's GB 22115-2008 standards differ from EU or US requirements. Some buyers opt for pre-neutralized versions to simplify formulation processes. Always request recent microbial challenge test data for your specific product matrix.
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