Kaempferol-7-O-β-D-glucoside
Overview
Kaempferol-7-O-β-D-glucoside is a naturally occurring flavonoid glycoside, chemically derived from kaempferol and glucose. It is found in various plants, including traditional herbs like Ginkgo biloba and Sophora japonica. This compound is of significant interest in biochemical and pharmaceutical research due to its bioactive properties, such as antioxidant and anti-inflammatory effects. In industrial applications, Kaempferol-7-O-β-D-glucoside is utilized in the development of nutraceuticals, functional foods, and cosmetic products. Its ability to modulate cellular pathways makes it a candidate for therapeutic research, particularly in areas like oxidative stress and chronic inflammation.
Physical and Chemical Properties
Kaempferol-7-O-β-D-glucoside appears as a yellow to light brown powder with a molecular weight of 448.38 g/mol. It is soluble in organic solvents like methanol and ethanol but has limited solubility in water. The compound exhibits stability under typical storage conditions but may degrade under prolonged exposure to light or high temperatures. Its melting point ranges between 180-185°C, and it is characterized by its flavonoid backbone, which contributes to its UV-absorbing properties. The glycosidic bond at the 7-position enhances its bioavailability compared to its aglycone form, kaempferol.
Main Applications
The primary applications of Kaempferol-7-O-β-D-glucoside are in pharmaceutical and nutraceutical industries. It is studied for its potential in managing oxidative stress-related disorders, such as cardiovascular diseases and neurodegenerative conditions. Its anti-inflammatory properties also make it a candidate for skincare formulations. In the food industry, this compound is used as a natural antioxidant additive to enhance the shelf life of products. Additionally, it is incorporated into dietary supplements aimed at promoting overall health and wellness due to its bioactive benefits.
Safety and Storage
Kaempferol-7-O-β-D-glucoside should be handled with standard laboratory precautions, including the use of gloves and protective eyewear. While it is not classified as highly hazardous, inhalation or skin contact with fine powder should be avoided to prevent irritation. For storage, the compound should be kept in a tightly sealed container in a cool, dry place, preferably at -20°C for long-term preservation. Exposure to moisture, light, or extreme temperatures should be minimized to maintain its stability and efficacy.
B2B Procurement Guide
When procuring Kaempferol-7-O-β-D-glucoside, it is essential to verify the purity of the compound, typically through HPLC or LC-MS analysis. Reputable suppliers should provide certificates of analysis (CoA) detailing purity, contaminants, and batch consistency. Buyers should also consider the supplier’s compliance with Good Manufacturing Practices (GMP) and their ability to provide technical support. Pricing varies based on purity and quantity, with bulk purchases often attracting discounts. Always request samples for preliminary testing before large-scale procurement.
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