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JWH-512

Updated: 2026-07-31

Overview

JWH-512 is a synthetic cannabinoid receptor agonist, part of the JWH series developed by John W. Huffman. It is primarily used in scientific research to study cannabinoid receptors and their effects. Due to its potency and structural similarity to THC, it has been subject to regulatory scrutiny in many jurisdictions. Researchers utilize JWH-512 to explore the pharmacological effects of cannabinoids, including their interaction with CB1 and CB2 receptors. Its use is restricted to controlled environments, and it is not approved for human consumption.

Physical and Chemical Properties

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JWH-512 is typically found as a white or off-white powder, soluble in organic solvents like ethanol and DMSO. Its exact molecular formula and weight are not widely disclosed, but it shares structural similarities with other synthetic cannabinoids in the JWH series. The compound's stability depends on proper storage conditions, including protection from light, moisture, and extreme temperatures. Its solubility profile makes it suitable for laboratory use, where precise dosing is required for experimental protocols.

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Main Applications

JWH-512 is predominantly used in research settings to investigate the mechanisms of cannabinoid receptors. Its high affinity for CB1 and CB2 receptors makes it a valuable tool for studying the endocannabinoid system. In addition to basic research, JWH-512 may be used in preclinical studies to assess the potential therapeutic effects of cannabinoids. However, its use is strictly limited to authorized laboratories due to its potent biological activity and regulatory status.

Safety and Storage

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Handling JWH-512 requires strict adherence to safety protocols, including the use of personal protective equipment (PPE) such as gloves and lab coats. The compound should be stored in a cool, dry place, away from light and moisture to maintain its stability. Due to its potential health risks, JWH-512 should only be used by trained professionals in controlled environments. Proper disposal methods must be followed to prevent environmental contamination and unintended exposure.

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B2B Procurement Guide

When procuring JWH-512, B2B buyers should verify the supplier's credibility and ensure compliance with local regulations. Reputable suppliers will provide certificates of analysis (CoA) and material safety data sheets (MSDS). Prices vary depending on the quantity and supplier, so it is advisable to request quotes from multiple sources. Buyers should also confirm the compound's purity and storage conditions before purchase to ensure it meets their research requirements.

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