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Isothiazolemethanol

Updated: 2026-08-03

Overview

Isothiazole methanol is an organic compound featuring an isothiazole ring bonded to a methanol group. It serves as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound's reactive hydroxyl group makes it valuable for further chemical modifications. Its applications span across industries, particularly in the development of antimicrobial agents and pesticides. Due to its moderate stability, it requires careful handling and storage to prevent degradation.

Physical and Chemical Properties

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Isothiazole methanol is a colorless to pale yellow liquid with a molecular weight of 115.15 g/mol. It is soluble in both water and organic solvents, facilitating its use in various chemical reactions. The compound's density is approximately 1.2 g/cm³, and it exhibits moderate stability under standard conditions. The reactive hydroxyl group on the isothiazole ring allows for easy functionalization, making it a preferred intermediate in synthetic chemistry. However, its reactivity also necessitates cautious handling to avoid unintended reactions or decomposition.

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Main Applications

Isothiazole methanol is primarily used as an intermediate in the pharmaceutical industry, where it contributes to the synthesis of antimicrobial and antifungal agents. Its role in agrochemicals includes the production of pesticides and herbicides, leveraging its bioactive properties. Additionally, the compound finds applications in research and development, particularly in the study of heterocyclic chemistry. Its versatility and reactivity make it a valuable tool for chemists exploring new molecular frameworks.

Safety and Storage

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Isothiazole methanol requires careful handling due to its reactive nature. Workers should use appropriate personal protective equipment (PPE), including gloves and goggles, to prevent skin contact and inhalation. The compound should be stored in a cool, dry place, away from direct sunlight and incompatible materials. In case of spills, immediate containment and cleanup are essential to minimize exposure. Proper disposal methods should be followed to ensure environmental safety. Always refer to the material safety data sheet (MSDS) for detailed safety guidelines.

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B2B Procurement Guide

When procuring isothiazole methanol, buyers should prioritize suppliers with a proven track record of quality and reliability. Request certificates of analysis (CoA) to verify purity and composition. Comparing prices from multiple suppliers can help secure competitive rates, but quality should not be compromised for cost. Assess the supplier's ability to provide consistent quantities and timely deliveries. Establishing long-term partnerships with reputable suppliers can ensure a steady supply chain. Additionally, consider the supplier's adherence to safety and regulatory standards.

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