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Isomaltose

Updated: 2026-07-15

Overview

Isomaltose, chemically known as 6-O-α-D-Glucopyranosyl-D-glucose, is a disaccharide derived from the partial hydrolysis of starch. It is structurally similar to maltose but with a different glycosidic linkage, which affects its digestibility and functional properties. Isomaltose is valued in the food and pharmaceutical industries for its low glycemic index and prebiotic effects. Unlike regular sugars, isomaltose is slowly digested, making it suitable for diabetic-friendly products. It also promotes the growth of beneficial gut bacteria, enhancing its appeal in functional foods and dietary supplements. Its non-cariogenic nature further makes it a preferred sweetener in oral care products.

Physical and Chemical Properties

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Isomaltose appears as a white crystalline powder with a sweet taste, though less intense than sucrose. It has a molecular weight of 342.30 g/mol and a melting point of approximately 140-145°C. The compound is highly soluble in water but only slightly soluble in ethanol, which influences its applications in liquid formulations. Its stability under moderate heat and pH conditions makes it suitable for baking and processed foods. The glycosidic bond in isomaltose resists enzymatic breakdown in the upper gastrointestinal tract, allowing it to reach the colon intact, where it acts as a prebiotic. This property is leveraged in probiotic and gut health products.

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Main Applications

In the food industry, isomaltose is used as a low-calorie sweetener and humectant in products like sugar-free candies, baked goods, and beverages. Its slow digestion helps maintain stable blood sugar levels, appealing to health-conscious consumers. The pharmaceutical sector utilizes isomaltose as an excipient in tablets and syrups due to its binding and stabilizing properties. It is also incorporated into oral rehydration solutions and infant formulas for its mild sweetness and digestibility. Additionally, its prebiotic effects are harnessed in dietary supplements aimed at improving gut microbiota balance.

Safety and Storage

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Isomaltose is classified as GRAS (Generally Recognized as Safe) by regulatory bodies, making it safe for consumption in recommended amounts. Excessive intake may lead to bloating or diarrhea, typical of non-digestible carbohydrates. For storage, isomaltose should be kept in a cool, dry environment, sealed tightly to prevent moisture absorption. Bulk storage in food-grade containers is advisable to maintain purity. Proper handling ensures longevity and prevents clumping, which can affect its usability in manufacturing processes.

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B2B Procurement Guide

When procuring isomaltose, buyers should prioritize suppliers who provide certificates of analysis (CoA) to verify purity and compliance with industry standards such as USP or FCC. Food-grade and pharmaceutical-grade variants are available, with the latter meeting stricter quality controls. Bulk purchases often yield cost savings, but storage capacity and shelf life should be considered. Partnering with reputable manufacturers ensures consistent quality and reliable supply chains. Buyers should also inquire about customization options, such as particle size or blend formulations, to suit specific application needs.

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