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Isolongifolene

Updated: 2026-07-21

Overview

Isolongifolene is a naturally occurring sesquiterpene derived primarily from pine resin or synthesized industrially. It is valued for its woody, amber-like scent and chemical stability, serving as a foundational ingredient in perfumery and flavor formulations. The compound’s unique structure also makes it a versatile intermediate in pharmaceutical synthesis. First isolated in the mid-20th century, isolongifolene gained prominence due to its low volatility and ability to enhance the longevity of fragrances. Its compatibility with other aroma chemicals further expands its utility in creating complex scent profiles.

Physical and Chemical Properties

异长叶烯 CAS 1135-66-6 包装1kg 25kg 合成中间体 含量98% 拉那白现货武汉拉那白医药化工有限公司

Isolongifolene is a colorless to pale yellow liquid with a density slightly lower than water. Its boiling point ranges between 265-267°C, and it is insoluble in water but miscible with common organic solvents like ethanol and ether. The compound exhibits exceptional thermal and oxidative stability, which is critical for its use in high-temperature applications. Key chemical properties include resistance to polymerization and minimal reactivity under standard conditions. These traits make it suitable for prolonged storage and integration into formulations requiring consistent performance over time.

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Main Applications

The primary use of isolongifolene is in the fragrance industry, where it acts as a fixative and base note in perfumes, soaps, and detergents. Its woody aroma blends well with citrus and floral scents, making it a staple in masculine and unisex fragrances. In pharmaceuticals, isolongifolene serves as a precursor for synthesizing active ingredients, particularly anti-inflammatory and antimicrobial agents. Additionally, it is employed in food flavoring to impart earthy undertones, though in strictly regulated quantities.

Safety and Storage

异长叶烯 CAS#1135-66-6 含量85% 克米克厂家包装1KG 25KG武汉克米克生物医药技术有限公司

Isolongifolene is classified as a combustible liquid and should be stored away from heat sources and open flames. Proper ventilation is essential to prevent vapor accumulation. Personal protective equipment (PPE), including gloves and goggles, is recommended during handling to avoid skin/eye contact. While not highly toxic, prolonged exposure to vapors may cause respiratory irritation. Spills should be contained with inert absorbents and disposed of following local hazardous waste regulations. Storage in amber glass or stainless steel containers minimizes degradation.

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B2B Procurement Guide

When sourcing isolongifolene, prioritize suppliers with ISO or GMP certifications to ensure quality consistency. Request detailed certificates of analysis (CoA) confirming purity (typically ≥95%) and the absence of heavy metals or residual solvents. Bulk pricing varies based on order volume and supplier location, with Asian manufacturers often offering competitive rates. Consider logistical factors like shipping temperature controls to preserve product integrity. Sample testing is advisable to verify odor profile and compatibility with end-use formulations.

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