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Isobutyl nitrite

Updated: 2026-08-03

Overview

Isobutyl nitrite is an organic compound belonging to the alkyl nitrite family. It is commonly used as a reagent in chemical synthesis and has applications in various industrial processes. Due to its volatile nature, it requires careful handling and storage. The compound is known for its rapid evaporation and distinct odor, which makes it easily identifiable in laboratory settings. Its primary role in chemical reactions often involves acting as a nitrosating agent, facilitating the introduction of nitroso groups into other molecules.

Physical and Chemical Properties

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Isobutyl nitrite is a colorless to pale yellow liquid with a molecular weight of 103.12 g/mol. It has a boiling point of 67-68°C and a density of 0.89 g/cm³. The compound is highly soluble in organic solvents like alcohol and ether but only slightly soluble in water. Its key chemical properties include high volatility and flammability, making it sensitive to heat and light. These characteristics necessitate strict storage conditions to prevent decomposition or accidental ignition.

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Main Applications

Isobutyl nitrite is primarily used in chemical synthesis as a nitrosating agent. It is employed in the production of various nitroso compounds, which are intermediates in pharmaceuticals and dyes. Additionally, it finds use in industrial applications where rapid reaction kinetics are required. In laboratory settings, it serves as a reagent for specific organic reactions, particularly those involving the introduction of nitroso groups. Its volatility and reactivity make it a valuable tool for researchers working on nitrosation processes.

Safety and Storage

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Due to its toxic and flammable nature, isobutyl nitrite must be handled with extreme caution. Exposure can occur through inhalation, ingestion, or skin contact, leading to irritation or more severe health effects. Proper personal protective equipment (PPE) is essential when working with this compound. Storage should be in a cool, dry, and well-ventilated area, away from heat sources and open flames. Containers must be tightly sealed to prevent evaporation and contamination. Spills should be managed immediately using appropriate absorbents and neutralizers.

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B2B Procurement Guide

When procuring isobutyl nitrite, buyers should prioritize suppliers with a proven track record of safety and regulatory compliance. Verify the CAS number (542-56-3) and purity specifications to ensure the product meets your requirements. Price ranges typically fall between $50 and $100 per liter, depending on purity and supplier. Bulk purchases may offer cost savings, but storage capacity and safety measures must be evaluated. Always request safety data sheets (SDS) and certificates of analysis (CoA) before finalizing orders.

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