Overview
Iodocyclopentane, also known as cyclopentyl iodide, is a halogenated organic compound with the molecular formula C5H9I. It is widely used in pharmaceutical and chemical industries as an intermediate in organic synthesis. The compound is characterized by its clear to pale yellow liquid appearance and high reactivity due to the presence of an iodine atom. Its primary role in chemical reactions involves acting as an alkylating agent, making it valuable for constructing more complex molecular structures. Due to its reactivity, it is often handled under controlled conditions to prevent unwanted side reactions.
Physical and Chemical Properties
Iodocyclopentane is a dense liquid with a boiling point of 150-152°C. It is soluble in common organic solvents such as ethanol and ether but is insoluble in water. The compound's high density (1.55 g/cm³) and halogen content contribute to its reactivity, particularly in nucleophilic substitution reactions. Its molecular weight is 196.03 g/mol, and it is typically stored in amber bottles to protect it from light degradation. The iodine atom in the molecule makes it a useful reagent for introducing cyclopentyl groups into other compounds.
Main Applications
Iodocyclopentane is primarily used in the pharmaceutical industry as an intermediate for synthesizing active pharmaceutical ingredients (APIs). It is also employed in organic chemistry research for constructing cyclopentyl-containing compounds. In addition to pharmaceuticals, it finds use in agrochemicals and specialty chemicals. Its ability to act as an alkylating agent makes it versatile for various synthetic pathways, including the production of cyclopentyl derivatives used in fragrances and flavors.
Safety and Storage
Iodocyclopentane is harmful if swallowed or inhaled and can cause skin and eye irritation. Proper personal protective equipment (PPE), including gloves and goggles, should be worn when handling this compound. It should be stored in a cool, dry place away from light and moisture to prevent degradation. Spills should be contained and cleaned up immediately using appropriate absorbent materials. Disposal must comply with local regulations for halogenated organic waste. Ventilation is essential when working with this compound to avoid inhalation of vapors.
B2B Procurement Guide
When procuring iodocyclopentane, buyers should prioritize suppliers with verified certifications and a track record of delivering high-purity chemicals. The reference price range is approximately $50-$100 per 100g, but bulk purchases may qualify for discounts. Key considerations include purity levels (typically 98% or higher), packaging options (e.g., amber glass bottles), and shipping conditions to ensure the compound's stability. Buyers should also assess supplier lead times and inventory availability to align with production schedules.
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