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Iodocyclohexane

Updated: 2026-07-23

Overview

Iodocyclohexane, also known as cyclohexyl iodide, is a halogenated organic compound primarily used as an intermediate in chemical synthesis. Its molecular structure consists of a cyclohexane ring substituted with an iodine atom, making it highly reactive in various organic reactions. This compound is particularly valuable in the pharmaceutical and agrochemical industries, where it serves as a building block for more complex molecules. Due to its reactivity, iodocyclohexane must be handled with care, and proper storage conditions are essential to maintain its stability.

Physical and Chemical Properties

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Iodocyclohexane is a clear to pale yellow liquid at room temperature, with a distinct odor. It has a density of 1.624 g/cm³ and a boiling point between 180-182°C. The compound is insoluble in water but dissolves readily in common organic solvents such as ethanol, ether, and chloroform. Its chemical reactivity is attributed to the iodine atom, which can participate in substitution and elimination reactions. Iodocyclohexane is sensitive to light and heat, which can lead to decomposition, so it is often stored in amber bottles or other light-resistant containers.

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Main Applications

The primary use of iodocyclohexane is as an intermediate in organic synthesis. It is employed in the production of pharmaceuticals, where it acts as a precursor for various active ingredients. Additionally, it is used in agrochemicals to create pesticides and herbicides. In research settings, iodocyclohexane is utilized in the study of reaction mechanisms and the development of new synthetic methodologies. Its versatility and reactivity make it a valuable tool for chemists working in both academic and industrial laboratories.

Safety and Storage

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Iodocyclohexane is classified as a hazardous substance due to its corrosive nature and potential health risks. It can cause severe skin and eye irritation upon contact and is harmful if inhaled or ingested. Proper personal protective equipment (PPE), including gloves, goggles, and lab coats, should always be worn when handling this compound. Storage requirements include keeping the substance in a cool, dry, and well-ventilated area, away from direct sunlight and heat sources. Containers should be tightly sealed and made of materials resistant to corrosion, such as glass or certain plastics.

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B2B Procurement Guide

When procuring iodocyclohexane, it is essential to consider factors such as purity, packaging, and supplier reliability. High-purity grades are often required for pharmaceutical applications, while technical grades may suffice for industrial uses. Suppliers should provide detailed certificates of analysis (CoA) to verify the product's specifications. Price ranges can vary significantly based on quantity, purity, and supplier location. Bulk purchases may offer cost savings, but storage capacity and shelf-life considerations must be taken into account. Always ensure that the supplier complies with local and international safety regulations.

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