Overview
Indane, chemically known as 2,3-dihydro-1H-indene, is a bicyclic hydrocarbon that serves as an important building block in organic chemistry. It consists of a benzene ring fused to a cyclopentane ring, giving it unique chemical properties that make it valuable for various industrial applications. This compound is typically produced through catalytic hydrogenation of indene or as a byproduct in petrochemical processes. Its relatively simple structure and reactivity have made it a versatile intermediate in the synthesis of more complex organic molecules.
Physical and Chemical Properties
Indane presents as a colorless to pale yellow liquid at room temperature with a characteristic aromatic odor. It has a density slightly lower than water (0.963 g/cm³) and a boiling point around 176-177°C, making it relatively easy to handle in laboratory and industrial settings. The compound exhibits typical hydrocarbon behavior, being insoluble in water but readily soluble in common organic solvents like ethanol, ether, and benzene. Its bicyclic structure provides stability while maintaining sufficient reactivity for chemical transformations, particularly in electrophilic aromatic substitution reactions.
Main Applications
In the pharmaceutical industry, indane serves as a key intermediate for synthesizing various active pharmaceutical ingredients (APIs), particularly those with fused ring systems. Its structure is found in several classes of therapeutic compounds, including nonsteroidal anti-inflammatory drugs and cardiovascular medications. The fragrance and flavor industry utilizes indane derivatives as components in perfumes and aroma chemicals. Additionally, it finds use in organic synthesis as a starting material for more complex polycyclic compounds, and in materials science for developing specialized polymers with unique properties.
Safety and Storage
As a flammable hydrocarbon, indane requires careful handling to prevent fire hazards. It should be stored in tightly sealed containers away from heat sources and open flames, preferably in a cool, well-ventilated area. Secondary containment is recommended for bulk storage. Personal protective equipment including chemical-resistant gloves and safety goggles should be worn when handling this compound. In case of skin contact, wash immediately with plenty of water. Proper ventilation is essential to prevent inhalation exposure, as the vapors may cause respiratory irritation at high concentrations.
B2B Procurement Guide
When procuring indane for industrial use, buyers should clearly specify purity requirements (typically 95-99%) and any particular grade needed for their application. Technical grade is sufficient for many synthetic applications, while pharmaceutical grade may be required for drug manufacturing. Suppliers typically offer indane in various packaging options ranging from small laboratory bottles (100mL-1L) to industrial drums (200L). Lead times can vary depending on market demand, so advance planning is recommended. Quality certificates of analysis should be requested to verify purity and confirm the absence of significant impurities that might affect downstream processes.
Related Manufacturers
- 主营：全氟三丁胺、异丙醇铝、纳米勃姆石、二苄叉山梨醇、六氟丙烯二聚体、六氟环氧丙烷二聚体、二异戊基硫醚、隐色结晶紫、邻菲罗啉
- 主营：磷钼酸、艾拉莫德中间体、光引发剂、6-二羟基吲哚、甲基丙二酸、聚二羟基吲哚、2-辛基十二醇、苯芴醇、溴芬酸钠中间体、樟脑醌、钼酸钾、丝素蛋白、盐酸胍、β-丙氨酸甲酯盐酸盐、7-去氢胆固醇、甘氨胆酸钠盐、半叶素、胆固醇、蛋白酶K、D-荧光素钾盐、光引发剂LAP、BIS-TRIS、甲基丙烯酸氧杂环丁烷
- 主营：全氟三丁胺、聚硅氮烷、特种硅油、全氟聚醚二醇、特种硅树脂
- 主营：甲酸镍、水苏糖、阻燃剂、柠檬醛、西瓜酮、氢醌酯、卡必醇、消泡剂、磷酸铁、肉桂醇、肉桂醛、碳酸镉、磷酸铝、银墨水、椰油胺、封装胶、化合物、桦木油、稀释剂、羟乙基、乙硫氮、润肤剂、球虫酯、矮壮素、异龙脑
- 主营：异辛醇、乳化剂、乙烯醚、聚乙二醇、氢化蓖麻油、醚羧酸、脂肪醇、分散剂、染色助剂、异构醇醚、泊洛沙姆、椰油酰胺、基羟乙基、烷基糖苷、特辛基酚、聚氧乙烯、嵌段聚醚、单油酸酯、异构十三醇、丙烯磺酸钠、丙烯酰胺基、醇醚葡糖苷、低泡渗透剂、甲酯乙氧基、癸基葡糖苷
- 主营：丙烯酸单体、月桂酸乙烯酯、月桂酸甲酯、双酚A二缩水甘油醚、六氟双酚 A、季戊四醇磷酸酯
- 主营：冲压油、异构烷烃、异构十一烷、茚满、医药中间体、清洗剂、缩水甘油醚、农药中间体
- 主营：氯菊酯、转移剂、聚酯树脂、二甲氧基、驱蚊原液、食品香料、缩水甘油酯、蚊香增效剂、丙烯酸缩水、环氧稀释剂、硅烷偶联剂、超疏水材料、对甲氧基苯酚、对羟基苯甲醚、乙烯基双封头、苯基缩水甘油醚
- 主营：二甲基亚砜、乙二醇、丙二醇、DMAC
- 主营：甜菊糖、氯乙酰、酞菁绿、二乙苯、二戊烯、4861-19-2、1192-62-7、8002-74-2、7782-61-8、2842-44-6、二聚酸、戊二醇、阻燃剂、4316-73-8、单甲醚、硫酸锂、大理石、羊脂酸、7783-40-6、磷酸氢、龙脑油、聚甘油、聚醚f68、磺化油、1310-58-3
- 主营：胆酸、半叶素、缩合剂、二羟基吲哚、生物缓冲液、表面活性剂、硅烷偶联剂、L-丙交酯、光电材料中间体、精细化工
- 主营：乙酸镁、阻燃剂、热熔胶、二氢化茚、聚合物、锂电池、光电极、泡泡糖、氯丁胶、碳酸镉、新癸酸、补差价、稀释剂、羟乙基、氧化铝、氧化铜、甲酸钾、c/c材料、碳酸锰、玻璃粉、硬光油、防腐剂、氧化铋、防水剂、聚丙烯、增粘树
- 主营：苯甲醛、酰亚胺、苯磺酸、二叔丁酯、磷酸二苯酯、二酸二乙酯、酸二异丙酯、二咪唑羰基、异丙基、cas-50-63-5、氨基丙基、试剂医药、化学醋酸、化学试剂、甲基硅基、盐酸羟胺、苯并三唑、苄基丙酮、试剂化工、丙烯酰氯、甲基乙炔、氮杂苯并、化学碳酸钾、中间体化工、医药中间体
- 主营：尼克酸、十六酸、阻燃剂、tpeg-2400、酸性橙、辛癸醇、乙酰肼、诱食剂、川芎油、十八酸、aha化妆、鞣花酸、防染盐、香茅醇、苯甲醇、松油醇、酪蛋白、磷酸氢、哑光粉、7647-14-5、滑石粉、拉丝剂、冷除油、氟甲苯、7783-03-1
- 主营：减磨剂、防锈剂、添加剂、润滑剂、抗腐剂、丙烯酸、抗氧剂、改进剂、清净剂、极压剂、色墨油墨、金属钝化剂、无灰分散剂、聚氨酯乳液、聚氨酯树脂、复合油墨树脂、高分子化合物、润滑脂拉丝剂、润滑油破乳剂、膜强度增强剂、润滑油增稠剂、润滑脂增粘剂、导热油复合剂、硫化烷基酚钙、活塞环释放剂