Overview
Imidazole is a heterocyclic organic compound with a five-membered ring structure containing two nitrogen atoms. It is a fundamental building block in many biologically active compounds and industrial chemicals. Imidazole and its derivatives are widely studied due to their presence in natural products like histidine and purines. Imidazole's versatility stems from its ability to act as a base, form hydrogen bonds, and participate in various chemical reactions. This makes it invaluable in pharmaceuticals, where it is used in antifungal agents, antihistamines, and other therapeutic drugs. Its stability and reactivity also make it useful in agrochemicals and corrosion inhibitors.
Physical and Chemical Properties
Imidazole is a white to pale yellow crystalline solid at room temperature. It has a melting point of 89-91 °C and a boiling point of 256 °C. The compound is soluble in water and common organic solvents like ethanol and ether, which facilitates its use in various chemical processes. Imidazole exhibits weak basicity due to the lone pair of electrons on one of its nitrogen atoms. It can form stable salts with acids and participates in electrophilic substitution reactions. The compound's aromaticity contributes to its stability and reactivity, making it a key intermediate in organic synthesis.
Main Applications
Imidazole is a critical component in the pharmaceutical industry, where it serves as a building block for drugs like ketoconazole and metronidazole. Its antifungal and antibacterial properties are leveraged in topical and systemic medications. In agrochemicals, imidazole derivatives are used as fungicides and plant growth regulators. The compound's ability to inhibit corrosion makes it valuable in industrial applications, particularly in metal treatment and coating formulations. Additionally, imidazole is used in the production of dyes, plastics, and other specialty chemicals.
Safety and Storage
Imidazole should be handled with care to avoid skin and eye irritation. Proper personal protective equipment (PPE), including gloves and goggles, is recommended when working with this compound. Ensure adequate ventilation to prevent inhalation of dust or vapors. Storage conditions for imidazole include a cool, dry, and well-ventilated area, away from strong oxidizing agents and acids. The compound should be kept in tightly sealed containers to prevent moisture absorption and contamination. In case of spills, use appropriate absorbent materials and dispose of them according to local regulations.
B2B Procurement Guide
When procuring imidazole for industrial or commercial use, consider purity grades, which typically range from 98% to 99.9%. Higher purity grades are essential for pharmaceutical applications, while technical grades may suffice for industrial uses. Verify supplier certifications, such as ISO or GMP compliance, to ensure product quality and consistency. Bulk purchases may offer cost advantages, but storage and handling logistics should be evaluated. Request material safety data sheets (MSDS) and certificates of analysis (CoA) to confirm specifications and safety data.
Related Manufacturers
- 主营：抗氧剂、乳化剂、苯扎氯铵、CN咪唑、烷基二甲基、氢化蓖麻油、表面活性剂、双链季胺盐、聚氧乙烯醚、二丁基羟基甲苯、甘油聚氧丙烯醚、十二烷基硫酸钠、树脂、助剂
- 主营：二十醇、钒酸酐、键合剂、环戊酮、甲醇钾、聚醚胺、正辛烷、三甲胺、二聚酸、双甲酮、戊二醇、异戊烷、正癸醇、新癸酸、清洗剂、磷酸酐、水合物、异戊醇、磷酸酯、异辛烷、氯化锌、化妆品、苯甲胺、水芹醛、正壬醇
- 主营：丙二胺、十四酸、棕榈酸、正壬胺、十烷酸、苯酰氯、醋酰胺、甲酸钠、工业级1、工业级e0、工业级mpd、十二叔胺、四氢呋喃、四甲撑硫、cyc环己酮、聚合醇胺、六氢苯酐、月桂酰胺、丙烯酰氯、十六叔胺、氯乙酰氯、盐酸羟胺、苯磺酰氯、蓖麻油酸、苯扎氯铵
- 主营：固体酸催化剂、重组胶原蛋白、硅油、甲基咪唑、特种硅油、聚硅氮烷、硼酸铝晶须、碳化硅晶须、t-BAMBP萃取剂、全氟三丁胺
- 主营：乙酸镁、阻燃剂、热熔胶、cn、聚合物、锂电池、光电极、泡泡糖、氯丁胶、碳酸镉、新癸酸、补差价、稀释剂、羟乙基、氧化铝、氧化铜、甲酸钾、c/c材料、碳酸锰、玻璃粉、硬光油、防腐剂、氧化铋、防水剂、聚丙烯、增粘树
- 主营：树脂合、木质素、分析纯、cn、化学试剂、涂覆金属、己二醇酯、油墨pu树脂、水性pu树脂、二乙二醇酯、二酸二甲酯、聚酯多元醇、树脂固化剂、水性聚氨酯、聚酰胺树脂、聚氨酯树脂、聚氨酯弹性体、水性喷墨打印、聚碳酸酯二醇、面料柔软整理、己二酸乙二醇、改性聚酰亚胺
- 主营：胶粘剂、地坪漆、防腐涂料、甲基咪唑、环氧树脂
- 主营：表面活性剂、十六碳二酸、防锈添加剂、液体咪唑促进剂、椰油醇醚硫酸钠、二硬脂酸乙烯酯
- 主营：化妆品原料、各种表面活性剂、纺织用化学原料
- 主营：发热板、甘氨酸、阻燃剂、甲基咪唑、深铬黄、胶黏剂、十八酸、正癸酸、羊脂酸、锂电池、光电极、消泡剂、丙酸铵、珠光片、油墨涂、赖氨酸、消光剂、水镁石、稀释剂、酸性红、羟乙基、梧桐胶、黄蜂蜡、abs树脂、铝钙石、脂肪酶
- 主营：固化剂、表面处理剂、无机矿物颜填料、液体咪唑促进剂、氨基硅烷偶联剂
- 主营：环氧树脂、助剂、丁腈橡胶、固化剂、增韧剂、润湿剂、二氧化硅
- 主营：咪唑、水性涂料油墨
- 主营：水苏糖、阻燃剂、玫瑰酯、液体咪唑促进剂价格、胶黏剂、硫酸锂、百里酚、羊脂酸、四氢萘、溴壬烷、琥珀芯、磷酸铵、锑酸钠、牛磺酸、灭火剂、碳酸镍、特戊醛、蒸煮剂、咖啡酸、熟化剂、浮选剂、稀释剂、西瓜酮、甜昧剂、去除剂、乙硫氮
- 主营：防闪锈剂、环氧树脂、防锈颜料、耐盐雾剂、防腐涂料、氟碳树脂、环氧乳液、环氧乳化剂、活性稀释剂、碳酸钙、硅土、涂料助剂、溶剂、苯甲醇、改性环氧、清洗剂、消毒液、增韧剂、特种涂料、异氰酸酯、中和剂、有机硅树脂、炭黑、水性环氧