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Hydroxyphenethylamine

Updated: 2026-08-05

Overview

Hydroxytyramine, commonly known as dopamine, is a catecholamine neurotransmitter and hormone. It is synthesized in the brain and adrenal glands and plays a crucial role in regulating mood, motivation, and motor control. Dopamine is also used in medical treatments for conditions like Parkinson's disease and shock. In industrial contexts, hydroxytyramine serves as a precursor in the synthesis of other bioactive compounds. Its significance in both biological and chemical fields makes it a valuable compound for research and pharmaceutical applications.

Physical and Chemical Properties

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Hydroxytyramine is a white to off-white crystalline powder with a molecular weight of 153.18 g/mol. It has a melting point of 128-131°C and is soluble in water, making it suitable for aqueous formulations. The compound is sensitive to oxidation, requiring careful handling and storage to maintain stability. The molecular structure of hydroxytyramine includes a catechol ring and an ethylamine side chain, which are critical for its biological activity. Its solubility in organic solvents like ethanol is limited, which influences its formulation in pharmaceutical products.

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Main Applications

Hydroxytyramine is primarily used in the pharmaceutical industry as a treatment for conditions such as Parkinson's disease, where dopamine deficiency occurs. It is also administered in cases of septic shock to improve blood pressure and cardiac output. In research, dopamine is employed to study neurological pathways and disorders. Additionally, it serves as a building block in the synthesis of other neurotransmitters and pharmaceutical agents, highlighting its versatility in both medical and chemical applications.

Safety and Storage

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Hydroxytyramine should be handled with care to avoid skin and eye irritation. Personal protective equipment, including gloves and goggles, is recommended during handling. The compound is sensitive to light and moisture, necessitating storage in a cool, dry environment. Proper storage conditions include airtight containers and protection from oxidative degradation. Disposal should follow local regulations for chemical waste to minimize environmental impact.

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B2B Procurement Guide

When procuring hydroxytyramine, verify the supplier's credentials and request certificates of analysis (CoA) to ensure purity and quality. Bulk purchases may offer cost advantages, but storage capacity and stability should be considered. Reliable suppliers often provide technical support and documentation, which is crucial for compliance in pharmaceutical and research applications. Comparing prices and lead times from multiple vendors can help optimize procurement strategies.

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