Hydroxymethylbenzamide

Updated: 2026-09-20

Overview

Hydroxymethylbenzamide is an organic compound with the molecular formula C8H9NO2. It is commonly used as an intermediate in the synthesis of pharmaceuticals and other fine chemicals. The compound is known for its stability and solubility in organic solvents, making it a versatile reagent in organic chemistry. In industrial settings, Hydroxymethylbenzamide is valued for its role in the production of active pharmaceutical ingredients (APIs). Its chemical structure allows for further functionalization, enabling the creation of more complex molecules. The compound is typically supplied as a white to off-white crystalline powder.

Physical and Chemical Properties

Hydroxymethylbenzamide is a crystalline solid with a molecular weight of 151.16 g/mol. It is soluble in common organic solvents such as ethanol and acetone but has limited solubility in water. The compound is stable under normal storage conditions but may degrade when exposed to extreme temperatures or prolonged moisture. The exact melting and boiling points of Hydroxymethylbenzamide are not widely documented, but it is known to decompose at elevated temperatures. Its density and other physical properties are typically provided by manufacturers based on batch-specific testing.

Main Applications

Hydroxymethylbenzamide is primarily used as an intermediate in the pharmaceutical industry. It serves as a building block for the synthesis of various drugs, including those targeting neurological and metabolic disorders. The compound's reactivity allows for the introduction of additional functional groups, facilitating the creation of complex molecules. In addition to pharmaceuticals, Hydroxymethylbenzamide finds applications in organic chemistry research. It is often employed in the development of new synthetic methodologies and as a reagent in multi-step reactions. Its versatility makes it a valuable tool for chemists working on drug discovery and material science.

Safety and Storage

Hydroxymethylbenzamide should be handled with care to avoid exposure. Personal protective equipment (PPE), including gloves and safety goggles, is recommended when working with the compound. Inhalation or ingestion can cause irritation, and skin contact should be avoided. For storage, the compound should be kept in a cool, dry place away from direct sunlight and moisture. Properly sealed containers are essential to prevent degradation. In case of spillage, the area should be cleaned immediately using appropriate absorbent materials and disposed of according to local regulations.

B2B Procurement Guide

When procuring Hydroxymethylbenzamide, B2B buyers should prioritize suppliers who provide detailed specifications and certificates of analysis (CoA). Purity levels, typically ranging from 95% to 99%, should be verified to ensure the compound meets the intended application requirements. Buyers should also consider the supplier's reputation, lead times, and compliance with international standards such as Good Manufacturing Practices (GMP). Bulk purchases may offer cost advantages, but storage conditions must be carefully managed to maintain product integrity. Custom synthesis options may be available for specialized applications.