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Hydroxymethyl Urea

Updated: 2026-07-18

Overview

Hydroxymethylallantoin is a derivative of allantoin, a naturally occurring compound found in many plants and animals. It is widely used in the cosmetics and personal care industry due to its skin-soothing and anti-irritant properties. The compound is synthesized through chemical modification of allantoin, enhancing its stability and efficacy in formulations. Hydroxymethylallantoin is particularly valued for its ability to promote wound healing, reduce skin irritation, and improve moisture retention. Its gentle yet effective nature makes it suitable for sensitive skin and products designed for individuals with skin conditions such as eczema or psoriasis.

Physical and Chemical Properties

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Hydroxymethylallantoin appears as a white crystalline powder with a molecular weight of 158.11 g/mol. It is soluble in water and slightly soluble in ethanol, making it easy to incorporate into aqueous formulations. The compound decomposes at approximately 230°C, and its stability under normal storage conditions is excellent. Key chemical properties include its ability to form hydrogen bonds, which contribute to its moisturizing effects. The hydroxymethyl group enhances its solubility and reactivity compared to allantoin, allowing for broader application in cosmetic and pharmaceutical products.

Main Applications

Hydroxymethylallantoin is primarily used in the cosmetics and personal care industry. It is a common ingredient in moisturizers, anti-aging creams, and products designed for sensitive or irritated skin. Its anti-inflammatory and keratolytic properties make it effective in treating conditions like eczema, psoriasis, and acne. In addition to skincare, hydroxymethylallantoin is used in hair care products to soothe the scalp and reduce irritation. Its compatibility with other ingredients and stability in formulations make it a versatile additive for a wide range of cosmetic products.

Safety and Storage

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Hydroxymethylallantoin is generally recognized as safe for topical use in cosmetics and personal care products. However, it is important to avoid inhalation or direct contact with eyes, as it may cause irritation. Proper handling procedures, including the use of gloves and protective eyewear, are recommended during formulation. Storage conditions should include a cool, dry environment away from direct sunlight to maintain the compound's stability. Bulk quantities should be stored in airtight containers to prevent moisture absorption and degradation.

B2B Procurement Guide

When procuring hydroxymethylallantoin for industrial or commercial use, buyers should prioritize suppliers with certifications such as ISO or GMP compliance. Purity levels should be verified through certificates of analysis, and the compound should meet relevant cosmetic or pharmaceutical standards. Price negotiations should consider bulk purchase discounts, but quality should not be compromised. Buyers should also evaluate supplier reliability, delivery timelines, and customer support to ensure a smooth procurement process.

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