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Hydroxykaurene

Updated: 2026-08-04

Overview

Kaurenoic acid, commonly referred to as ent-kaur-16-en-19-oic acid, is a diterpenoid compound naturally occurring in various plant species. It is particularly notable for its potential pharmacological properties, which have attracted interest in both traditional medicine and modern pharmaceutical research. The compound is often extracted from plants belonging to the Asteraceae family, where it serves as a secondary metabolite. Its unique chemical structure and bioactive potential make it a subject of ongoing scientific investigation.

Physical and Chemical Properties

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Kaurenoic acid is characterized by its diterpenoid backbone, which includes a carboxylic acid functional group. It typically appears as a white to off-white crystalline powder with a melting point around 160-165°C. The compound is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) but exhibits limited solubility in water. Its molecular weight is approximately 302.45 g/mol, and its stability is influenced by storage conditions, requiring protection from light and moisture.

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Main Applications

Kaurenoic acid is primarily used in pharmaceutical research due to its potential anti-inflammatory and antimicrobial properties. It has been studied for its role in modulating immune responses and inhibiting bacterial growth. In traditional medicine, extracts containing kaurenoic acid have been used for their purported therapeutic effects. The compound is also explored for its potential applications in cosmetic formulations and as a natural bioactive agent.

Safety and Storage

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Kaurenoic acid should be handled with care to avoid inhalation or direct skin contact. Appropriate personal protective equipment, such as gloves and lab coats, is recommended when working with this compound. Storage conditions are critical for maintaining stability. The compound should be kept in a cool, dry place, protected from light and moisture. Proper labeling and secure containers are essential to prevent accidental exposure or degradation.

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B2B Procurement Guide

When procuring kaurenoic acid, it is important to verify the purity and quality of the product. Suppliers should provide certificates of analysis (CoA) to confirm the compound's specifications. Consider regulatory requirements, especially if the compound is intended for pharmaceutical or cosmetic use. Pricing can vary significantly based on purity and supplier, so obtaining multiple quotes is advisable. Establishing long-term relationships with reputable suppliers can ensure consistent quality and reliability.

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