Overview
Hydroxyevodiamine Standard is a purified alkaloid compound isolated from Evodia rutaecarpa, a plant used in traditional medicine. As a certified reference material (CRM), it serves as a critical tool for quality assurance in pharmaceutical and biochemical research. The standard is characterized by its high purity and stability, ensuring reliable performance in analytical applications such as HPLC and mass spectrometry. In B2B transactions, this standard is typically supplied to research institutions, pharmaceutical manufacturers, and contract laboratories. Its role in method validation and compound identification makes it indispensable for regulatory compliance and drug development workflows. The compound's bioactive properties also attract interest for potential therapeutic applications, though such uses remain under investigation.
Physical and Chemical Properties
Hydroxyevodiamine presents as a white to off-white crystalline powder with a molecular weight of 319.36 g/mol. Its melting point ranges between 200-205°C, indicating moderate thermal stability. The compound is soluble in organic solvents like methanol and DMSO but exhibits limited solubility in water, a factor influencing its formulation and analytical preparation. Key chemical properties include its alkaloid structure, featuring a quinazoline core, which contributes to its bioactivity. The standard is typically supplied with ≥98% purity, verified by chromatographic methods. Stability is maintained under recommended storage conditions (2-8°C, protected from light), with degradation risks including oxidation and hygroscopicity in suboptimal environments.
Main Applications
The primary use of Hydroxyevodiamine Standard is as a reference material in analytical chemistry. It enables precise quantification and identification of hydroxyevodiamine in complex matrices, such as herbal extracts or pharmaceutical formulations, via techniques like HPLC-UV or LC-MS. This ensures batch-to-batch consistency and compliance with pharmacopeial standards. Beyond analytics, the compound is studied for its bioactive potential, including anti-inflammatory and neuroprotective effects. Research institutions procure the standard for in vitro and in vivo studies exploring its mechanisms of action. However, commercial therapeutic applications remain speculative, pending further clinical validation.
Safety and Storage
As a laboratory chemical, Hydroxyevodiamine Standard requires safe handling practices. Personal protective equipment (PPE), including gloves and safety goggles, is recommended to prevent skin contact or inhalation. While acute toxicity data may be limited, treating the compound as a potential irritant aligns with general alkaloid safety protocols. Storage demands strict adherence to temperature control (2-8°C) and protection from light to prevent degradation. Suppliers often ship the material with desiccants to mitigate moisture absorption. Long-term stability is maximized by aliquoting the powder to minimize repeated exposure to ambient conditions.
B2B Procurement Guide
Procuring Hydroxyevodiamine Standard necessitates attention to supplier credentials and product documentation. Buyers should prioritize vendors with ISO 17034 accreditation for reference materials, ensuring traceability and metrological reliability. Critical documents include a Certificate of Analysis (COA) detailing purity, testing methods, and batch-specific data. Pricing varies by purity grade and quantity, with bulk purchases (e.g., 100mg+) often reducing per-unit costs. Lead times may extend for custom purification requests. Importers must verify compliance with regional regulations, such as REACH or USP standards, to avoid logistical delays. Sample testing before large-scale orders is advisable to confirm suitability for intended applications.
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