Overview
10-Hydroxydecanoic acid (10-HDA) is a hydroxylated fatty acid derived from decanoic acid. It is primarily used as an intermediate in pharmaceutical synthesis and as an ingredient in cosmetics. Its unique chemical structure makes it valuable for producing esters and other derivatives. Industrially, 10-HDA is synthesized through controlled oxidation or microbial fermentation processes. Its applications span across multiple sectors, including healthcare, personal care, and specialty chemicals, due to its biocompatibility and functional versatility.
Physical and Chemical Properties
10-Hydroxydecanoic acid appears as a white crystalline powder with a melting point of 80-82°C. It is hydrophobic, dissolving readily in organic solvents like ethanol but only minimally in water. The presence of a hydroxyl group at the 10th carbon position enhances its reactivity for esterification and other chemical modifications. The compound is stable under standard storage conditions but may degrade when exposed to prolonged heat or strong oxidizers. Its molecular weight of 188.26 g/mol and linear carbon chain contribute to its moderate volatility and compatibility with lipid-based formulations.
Main Applications
In pharmaceuticals, 10-HDA serves as a precursor for synthesizing prodrugs and bioactive compounds. Its hydroxyl group enables conjugation with other molecules, improving drug delivery or bioavailability. The cosmetic industry utilizes it as an emollient or moisturizing agent in creams and lotions. Additionally, 10-HDA is employed in chemical research to develop polymers and surfactants. Its biodegradability and low toxicity make it suitable for eco-friendly applications, such as green solvents or lubricant additives.
Safety and Storage
While 10-Hydroxydecanoic acid is not highly hazardous, proper handling precautions are necessary. Use gloves and goggles to avoid skin or eye irritation. Ensure adequate ventilation to prevent inhalation of dust during processing. Store the compound in a tightly sealed container, away from direct sunlight and moisture. Ideal storage temperatures range between 15-25°C. Bulk quantities should be kept in a dry, well-ventilated area, segregated from strong oxidizers or reactive chemicals.
B2B Procurement Guide
When sourcing 10-Hydroxydecanoic acid, prioritize suppliers with ISO or GMP certifications to guarantee quality. Request a Certificate of Analysis (COA) specifying purity (typically 95-99%) and impurity profiles. Compare prices from multiple vendors, as costs vary based on batch size and purity grade. For large-scale procurement, negotiate long-term contracts to secure stable pricing. Verify logistics options, as some suppliers may offer temperature-controlled shipping for sensitive chemicals. Always confirm regulatory compliance for your region, especially if the compound will be used in pharmaceuticals or cosmetics.
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