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Hydroxybenzaldehyde oxime

Updated: 2026-07-23

Overview

Hydroxybenzaldehyde oxime is an organic compound derived from the condensation of hydroxybenzaldehyde and hydroxylamine. It is primarily used as an intermediate in chemical synthesis and as a chelating agent in various industrial processes. The compound's ability to form stable complexes with metal ions makes it valuable in analytical chemistry and pharmaceutical applications. Hydroxybenzaldehyde oxime is typically available as a white to off-white crystalline powder. Its molecular structure includes both hydroxyl and oxime functional groups, which contribute to its reactivity and versatility in chemical reactions. The compound is commonly synthesized in laboratories and is also available from commercial chemical suppliers.

Physical and Chemical Properties

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Hydroxybenzaldehyde oxime has a molecular formula of C7H7NO2 and a molecular weight of 137.14 g/mol. It appears as a white to off-white crystalline powder and is soluble in organic solvents such as ethanol and acetone. The compound exhibits slight solubility in water, which can vary depending on temperature and pH conditions. The oxime functional group in hydroxybenzaldehyde oxime is responsible for its chelating properties, enabling it to form stable complexes with metal ions. This property is particularly useful in analytical chemistry for the detection and quantification of metal ions. The compound's melting and boiling points are not well-documented, but it is known to decompose at elevated temperatures.

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Main Applications

Hydroxybenzaldehyde oxime is widely used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its chelating properties make it a valuable reagent in analytical chemistry, particularly for the detection of metal ions such as copper, nickel, and iron. In the pharmaceutical industry, hydroxybenzaldehyde oxime serves as a building block for the synthesis of drugs and active pharmaceutical ingredients (APIs). It is also employed in the production of corrosion inhibitors and as a stabilizer in polymer manufacturing. The compound's versatility and reactivity make it a key component in various industrial processes.

Safety and Storage

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Hydroxybenzaldehyde oxime should be handled with care to avoid skin and eye contact, as it may cause irritation. Proper personal protective equipment (PPE), including gloves and safety goggles, should be worn when working with this compound. In case of contact, rinse immediately with plenty of water and seek medical attention if necessary. The compound should be stored in a cool, dry place away from direct sunlight and moisture. It is recommended to keep the container tightly sealed to prevent contamination and degradation. Proper storage conditions help maintain the compound's stability and shelf life.

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B2B Procurement Guide

When procuring hydroxybenzaldehyde oxime for industrial or laboratory use, it is essential to verify the purity and quality of the product. Reputable suppliers should provide certificates of analysis (CoA) to confirm the compound's specifications. Bulk orders may offer cost advantages, but buyers should ensure that storage and handling requirements are met. Procurement professionals should also consider the supplier's reliability and track record. Established chemical suppliers with good industry reputations are preferable. Additionally, buyers should inquire about packaging options, lead times, and shipping conditions to ensure the product arrives in optimal condition.

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