Overview
Hydroxyapatite (HAp) powder is a calcium phosphate compound that mimics the mineral component of human bones and teeth. Its chemical formula is Ca5(PO4)3(OH), and it is the primary inorganic constituent of mammalian hard tissues. Due to its exceptional biocompatibility and osteoconductive properties, hydroxyapatite powder has become a critical material in biomedical engineering, dentistry, and cosmetics. It is synthesized through wet chemical precipitation, hydrothermal methods, or derived from natural sources like bovine bone.
Physical and Chemical Properties
Hydroxyapatite powder appears as a fine white powder with a density of 3.08-3.16 g/cm³. It is thermally stable up to 1100-1200°C, beyond which it decomposes into other calcium phosphate phases. The material is practically insoluble in water but dissolves in acidic solutions, making it useful for controlled drug release systems. Its crystalline structure allows for ion substitution, enabling the incorporation of trace elements like magnesium or strontium to modify its properties for specific applications.
Main Applications
In biomedical fields, hydroxyapatite powder is used for bone graft substitutes, dental implants, and coatings for metallic prostheses to improve osseointegration. Its porous forms serve as scaffolds for tissue engineering. The cosmetic industry utilizes nano-hydroxyapatite in toothpaste and skincare products for its remineralizing properties. Industrial applications include water treatment for heavy metal removal and chromatography media for protein purification.
Safety and Storage
While hydroxyapatite is non-toxic and biocompatible, powder form requires careful handling to prevent dust inhalation. Use appropriate PPE including dust masks and gloves. Store in tightly sealed containers at room temperature, away from moisture and acidic vapors. For medical-grade products, maintain sterility and track lot numbers for traceability. Shelf life is typically 2-3 years when properly stored.
B2B Procurement Guide
When sourcing hydroxyapatite powder, specify required parameters: purity (typically 95-99.9%), particle size (nanoscale to micron-range), crystallinity, and whether it's synthetic or natural-derived. For medical applications, request ISO 13485 or USP certification documentation. Bulk buyers should negotiate pricing tiers, with quantities over 100kg often receiving 15-30% discounts. Consider suppliers offering customized surface treatments or composite formulations.
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