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HMPPA

Updated: 2026-07-31

Overview

Hydroxymethylphenylphenylacetone (HMPPA) is an organic compound primarily used as an intermediate in pharmaceutical and chemical synthesis. Its molecular structure includes a hydroxymethyl group attached to a phenylphenylacetone backbone, making it a versatile building block for various industrial applications. HMPPA is known for its stability and reactivity, which makes it suitable for use in complex organic reactions. It is typically supplied as a crystalline powder and requires careful handling due to its chemical properties.

Physical and Chemical Properties

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HMPPA is characterized by its pale yellow to white crystalline appearance and a molecular weight of 240.30 g/mol. It has a melting point range of approximately 100-105°C and is soluble in common organic solvents such as ethanol and acetone. The compound is stable under normal storage conditions but can react with strong oxidizing agents. Its solubility and reactivity profile make it a valuable component in synthetic chemistry, particularly in the production of pharmaceuticals and specialty chemicals.

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Main Applications

HMPPA is widely used as an intermediate in the synthesis of pharmaceuticals, where it serves as a precursor for active pharmaceutical ingredients (APIs). Its role in organic synthesis extends to the production of complex molecules for research and industrial purposes. In addition to pharmaceuticals, HMPPA is utilized in the manufacture of specialty chemicals, including dyes, fragrances, and other fine chemicals. Its versatility and reactivity make it a preferred choice for chemists and manufacturers in these fields.

Safety and Storage

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Proper handling of HMPPA is essential to ensure safety in the workplace. The compound should be stored in a cool, dry place, away from direct sunlight and moisture. Containers must be tightly sealed to prevent contamination and degradation. Personal protective equipment (PPE), including gloves, goggles, and lab coats, should be worn when handling HMPPA. In case of exposure, immediate washing with water and seeking medical advice is recommended. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety instructions.

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B2B Procurement Guide

When procuring HMPPA, it is crucial to partner with reputable suppliers who adhere to strict quality and safety standards. Buyers should request certificates of analysis (CoA) and MSDS to verify the product's purity and handling requirements. Prices for HMPPA can vary based on quantity, purity, and supplier. Bulk purchases may offer cost advantages, but buyers should also consider storage and handling logistics. Establishing long-term relationships with reliable suppliers can ensure consistent quality and timely delivery.

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