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Hexanoic Anhydride

Updated: 2026-08-02

Overview

Hexanoic Anhydride, also known as Caproic Anhydride, is a chemical compound primarily used in organic synthesis. It is a derivative of hexanoic acid and is characterized by its high reactivity, making it a valuable reagent in the production of esters and other organic compounds. The compound is typically a colorless to pale yellow liquid with a distinct odor. Hexanoic Anhydride is widely utilized in the pharmaceutical and fragrance industries due to its ability to form esters, which are key components in many products. Its applications extend to the synthesis of plasticizers, lubricants, and other specialty chemicals. The compound's reactivity and versatility make it a staple in many chemical laboratories and industrial processes.

Physical and Chemical Properties

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Hexanoic Anhydride has a molecular formula of C12H22O3 and a molecular weight of 214.30 g/mol. It appears as a colorless to pale yellow liquid with a density of 0.93 g/cm³ at 25°C. The compound has a boiling point range of 220-222°C and is insoluble in water but soluble in common organic solvents such as ethanol and ether. Chemically, Hexanoic Anhydride is highly reactive, particularly in esterification reactions. It reacts readily with alcohols to form esters, a property that is exploited in various industrial applications. The anhydride is also sensitive to moisture and should be stored under dry conditions to prevent hydrolysis, which can degrade its effectiveness.

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Main Applications

Hexanoic Anhydride is predominantly used in the synthesis of esters, which are essential in the production of fragrances, flavors, and pharmaceuticals. Its ability to react with alcohols to form esters makes it a valuable reagent in these industries. Additionally, the compound is used in the manufacture of plasticizers and lubricants, where its chemical properties enhance product performance. In the pharmaceutical sector, Hexanoic Anhydride is employed in the synthesis of active pharmaceutical ingredients (APIs) and other intermediates. Its role in the fragrance industry involves the creation of ester-based scents that are used in perfumes and cosmetics. The compound's versatility ensures its continued demand across multiple sectors.

Safety and Storage

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Hexanoic Anhydride is a corrosive substance that can cause severe irritation to the skin, eyes, and respiratory system. Proper handling procedures, including the use of gloves, goggles, and protective clothing, are essential when working with this chemical. In case of contact, immediate washing with plenty of water is recommended, and medical attention should be sought if irritation persists. Storage of Hexanoic Anhydride requires a cool, dry environment away from moisture and oxidizing agents. The compound should be kept in tightly sealed containers to prevent exposure to air, which can lead to hydrolysis. Proper labeling and segregation from incompatible substances are also critical to ensure safety in the workplace.

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B2B Procurement Guide

When procuring Hexanoic Anhydride, it is important to verify the supplier's credentials and request material safety data sheets (MSDS) and certificates of analysis (CoA) to ensure product quality and compliance with safety standards. Bulk purchases may offer cost advantages, but buyers should assess storage capabilities to maintain the compound's integrity. Quality control is paramount, and buyers should consider conducting independent lab tests to confirm purity and consistency. Establishing long-term relationships with reputable suppliers can ensure a steady supply chain and competitive pricing. Additionally, buyers should stay informed about regulatory changes that may impact the procurement or use of Hexanoic Anhydride.

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