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Hexane

Updated: 2026-08-06

Overview

Hexane is a straight-chain alkane with six carbon atoms, primarily derived from petroleum refining. It is a versatile solvent due to its non-polar nature and low boiling point, making it ideal for industrial processes like oil extraction and adhesive formulation. In laboratories, hexane is commonly used for chromatography and as a reaction medium. Its widespread use in manufacturing and research underscores the need for strict handling protocols to mitigate flammability and toxicity risks.

Physical and Chemical Properties

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Hexane is a colorless liquid with a faint, gasoline-like odor. Its low density and viscosity facilitate easy mixing with other non-polar compounds. The substance evaporates rapidly at room temperature, contributing to its flammability (flash point: -22°C). Chemically, hexane is inert under standard conditions but reacts violently with strong oxidizers. Its insolubility in water and high vapor pressure necessitate careful containment to prevent environmental release.

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Main Applications

The largest industrial use of hexane is in soybean and other vegetable oil extraction, where it dissolves fats efficiently. It also serves as a cleaning agent for textiles and metal parts, and as a thinner for adhesives in footwear and furniture production. In pharmaceuticals, hexane aids in tablet coating and pesticide formulation. Specialty grades are employed in analytical chemistry for sample preparation and instrument calibration.

Safety and Storage

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Hexane poses significant health hazards, including central nervous system depression and dermatitis. Work areas must have explosion-proof equipment and continuous ventilation to limit airborne concentrations below OSHA's permissible exposure limit (500 ppm). Storage tanks should be grounded to prevent static sparks, and containers must bear GHS-compliant labels warning of flammability and toxicity. Spill kits with inert absorbents like vermiculite are essential for emergency response.

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B2B Procurement Guide

Bulk buyers should prioritize suppliers with ISO 9001 certification and batch-specific Certificates of Analysis (CoA). Technical hexane (60-70% purity) suits industrial applications, while HPLC-grade (≥99%) is mandatory for laboratories. Logistics planning must account for hazardous material shipping regulations (e.g., UN 1208 classification). Negotiate contracts with flexibility for volume discounts and just-in-time delivery to minimize on-site storage risks.

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