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Guanidine Acetate

Updated: 2026-07-29

Overview

Guanidinoacetic acid (GAA) is an organic compound that plays a critical role in the biosynthesis of creatine, a molecule essential for energy metabolism in muscles and the brain. Naturally occurring in the body, GAA is synthesized in the kidneys and liver from glycine and arginine. Industrially, it is produced as a white crystalline powder for use in animal feed and dietary supplements. GAA is widely recognized for its ability to enhance muscle growth and energy efficiency in livestock, poultry, and aquaculture. As a cost-effective alternative to direct creatine supplementation, it has gained popularity in the animal nutrition industry. Its safety and efficacy have been validated by numerous studies, making it a preferred choice for B2B buyers in the agricultural sector.

Physical and Chemical Properties

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Guanidinoacetic acid is characterized by its white crystalline appearance and high solubility in water, which facilitates its incorporation into liquid and solid feed formulations. The compound has a molecular weight of 117.11 g/mol and decomposes at around 300°C, indicating its stability under normal storage and handling conditions. Its chemical structure includes a guanidine group attached to an acetic acid moiety, which is pivotal for its role in creatine synthesis. GAA is slightly soluble in ethanol but insoluble in non-polar solvents. These properties make it versatile for various industrial applications, particularly in animal nutrition where it is often mixed with other feed ingredients.

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Main Applications

The primary application of guanidinoacetic acid is as a feed additive in the livestock and poultry industries. It serves as a precursor to creatine, which is vital for muscle energy metabolism. By supplementing animal diets with GAA, producers can improve growth rates, feed efficiency, and overall muscle mass in animals such as pigs, chickens, and fish. In addition to its use in animal feed, GAA is also explored as a dietary supplement for pets and performance animals like racehorses. Research suggests potential benefits in human nutrition, particularly for athletes and individuals with creatine deficiencies, though these applications are still under investigation.

Safety and Storage

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Guanidinoacetic acid is generally considered safe for use in animal feed, with regulatory approvals in many countries. It is classified as GRAS (Generally Recognized As Safe) by the FDA when used according to guidelines. However, standard laboratory precautions should be followed during handling to avoid inhalation or skin contact. For storage, GAA should be kept in a cool, dry environment away from moisture and direct sunlight to prevent degradation. Properly sealed containers are recommended to maintain product integrity. Bulk storage should avoid exposure to high temperatures or humidity, which could compromise the compound's efficacy.

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B2B Procurement Guide

When procuring guanidinoacetic acid for industrial or agricultural use, buyers should prioritize suppliers with certifications for feed-grade quality. Key factors to consider include purity levels (typically 98% or higher), CAS number verification, and compliance with regional regulations for animal feed additives. Price ranges vary based on quantity and purity, with bulk purchases often attracting discounts. Buyers are advised to request product samples and certificates of analysis (CoA) to ensure consistency and quality. Partnering with reputable manufacturers or distributors can mitigate risks associated with substandard products.

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