Overview
Fraxin is a naturally occurring coumarin glycoside primarily extracted from the bark of Fraxinus species, such as Fraxinus rhynchophylla. It has been used in traditional Chinese medicine for its therapeutic properties. Modern research has identified fraxin as a compound with potential anti-inflammatory, antioxidant, and neuroprotective effects, making it a subject of interest in pharmaceutical and nutraceutical industries. Derived from plant sources, fraxin is part of a broader class of coumarins, which are known for their diverse biological activities. Its glucoside structure enhances its solubility in water, which is advantageous for formulation in medicinal and research applications.
Physical and Chemical Properties
Fraxin is a white to off-white crystalline powder with a molecular weight of 370.31 g/mol. It has a melting point of approximately 220-222°C and is soluble in water, methanol, and ethanol. These properties make it suitable for various extraction and purification processes. The compound's structure includes a coumarin backbone with a glucoside moiety, contributing to its solubility and bioavailability. Its stability under normal storage conditions (cool, dry, and protected from light) ensures its longevity in both research and commercial settings.
Main Applications
Fraxin is primarily used in pharmaceutical research due to its bioactive properties. Studies suggest it may help reduce inflammation and oxidative stress, making it a candidate for developing treatments for chronic diseases. It is also explored in traditional medicine for its potential benefits in managing conditions like arthritis and neurodegenerative disorders. In the nutraceutical industry, fraxin is sometimes included in dietary supplements for its antioxidant effects. However, its use in commercial products is still limited and requires further clinical validation.
Safety and Storage
While fraxin is generally considered safe for research purposes, proper handling is essential to avoid potential risks. Direct contact or inhalation should be minimized, and personal protective equipment (PPE) such as gloves and masks should be used when handling the compound. Storage recommendations include keeping fraxin in a cool, dry place away from light and moisture to maintain its stability. Long-term storage may require desiccants or inert atmospheres to prevent degradation.
B2B Procurement Guide
When procuring fraxin for B2B purposes, buyers should prioritize suppliers who provide detailed certificates of analysis (CoA) to verify purity and quality. Regulatory compliance, such as adherence to Good Manufacturing Practices (GMP), is crucial for ensuring product safety and efficacy. Price ranges vary based on purity levels and supplier reputation. Bulk purchases may offer cost advantages, but buyers should confirm batch consistency and stability data before large-scale procurement.
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