Food Grade d-Biotin Powder
Overview
Food-grade D-biotin powder, a biologically active form of vitamin B7, is a critical micronutrient involved in fatty acid synthesis, glucose metabolism, and amino acid catabolism. Synthesized to meet pharmaceutical and food safety standards, it is widely incorporated into human and animal nutrition products due to its role in maintaining healthy skin, hair, and nails. As a coenzyme for carboxylases, biotin supports enzymatic reactions essential for cellular energy production. Its stability under typical food-processing conditions (e.g., heat, pH variations) makes it ideal for fortification in baked goods, beverages, and supplements.
Physical and Chemical Properties
D-biotin exhibits high thermal stability, with a melting point of 232–233°C before decomposition. Its crystalline structure ensures minimal degradation during storage when kept in airtight containers under recommended conditions (below 25°C, <60% humidity). The compound is sparingly soluble in organic solvents but readily dissolves in water (approximately 22 mg/mL at 25°C), facilitating its use in liquid formulations. UV-Vis spectroscopy typically confirms its purity, with a maximum absorbance at 234 nm in neutral aqueous solutions.
Main Applications
In the food industry, D-biotin is added to infant formulas, cereals, and energy bars to address dietary deficiencies. Clinical studies support its efficacy in managing biotinidase deficiency and improving brittle nail syndrome at doses of 2.5–5 mg/day. Animal feed manufacturers incorporate biotin (0.1–2 mg/kg feed) to enhance livestock hoof strength and poultry feathering. Cosmetic formulations leverage its topical benefits for hair growth serums and anti-aging creams, often combined with zinc or keratin.
Safety and Storage
D-biotin is non-toxic at recommended dosages, with an LD50 >10 g/kg in rodents. However, excessive intake (≥5 mg/day for humans) may interfere with lab test results, such as thyroid or hormone assays. Industrial handlers should use PPE to prevent dust inhalation. Long-term stability requires protection from oxidative degradation. Suppliers often nitrogen-flush packaging or include desiccants to maintain potency. Bulk shipments should be palletized to avoid moisture exposure during transit.
B2B Procurement Guide
Buyers should prioritize suppliers with ISO 9001 or NSF certification to ensure compliance with food safety standards (e.g., 21 CFR 184.1090 in the US). Key purchase criteria include HPLC-verified purity (≥98%), low heavy metal content (<10 ppm), and absence of Salmonella/E. coli. For cost efficiency, consider contract manufacturing agreements with MOQs of 25–100 kg. Spot prices fluctuate based on raw material (fumaric acid) availability. South Asian manufacturers often offer competitive rates, but verify COAs and export documentation for customs clearance.
Related Manufacturers
- 主营：甘氨酸、胍基乙酸、牛磺酸、L-精氨酸、食品级亚硫酸氢钠、魔芋粉、可可粉、L-抗坏血酸/vc、沙蒿胶、黄原胶、卡拉胶、瓜尔豆胶、半胱氨酸、氨基丁酸、苯丙氨酸、谷氨酰胺、酪蛋白酸钠、胱氨酸、色氨酸、肌酸、富硒酵母、富铬酵母、氯化胆碱、亮氨酸、干酪素/酪蛋白
- 主营：饲料添加剂、营养强化剂、增稠剂、食品添加剂、乳清蛋白粉、L-半胱氨酸、L-苯丙氨酸、L-异亮氨酸、乳化剂、防腐剂、色素、磷酸盐保水剂、黄原胶、甘氨酸、酪蛋白酸钠、大豆分离蛋白、海藻酸钠、丝氨酸、谷氨酰胺
- 主营：海藻酸钠、乳酸链球菌素、卡拉胶、L-硒-甲基硒代半胱、温轮胶、黄原胶、苯丙氨酸、亮氨酸、苏氨酸、谷氨酸、蛋氨酸、牛磺酸、谷氨酰胺、半胱氨酸、酪蛋白酸钠、柑橘黄、羧甲基纤维素钠、聚丙烯酸钠、柠檬酸、氨基丁酸、胍基乙酸、定优胶、干酪素
- 主营：威兰胶、古尔胶、瓜尔胶、L-精氨酸、L-抗坏血酸、L-蛋氨酸、L-半胱氨酸、L-半胱氨酸盐酸盐、L-谷氨酰胺、L-苯丙氨酸、DL-蛋氨酸、L-丙氨酸、瓜尔豆胶、甘氨酸、半胱氨酸、维生素C/vc、核黄素(维生素B2)、胍基乙酸、牛磺酸、工业级VC、酪蛋白酸钠、酪蛋白/干酪素、海藻酸钠/海藻酸钠、硒代蛋氨酸、烟酸/烟酰胺
- 主营：甜菊糖、甘氨酸、甘露糖、韦兰胶、海藻糖、植酸/植酸钠、威兰胶、魔芋胶、海藻酸钠、木糖醇、赤鲜糖醇、胱氨酸、精氨酸、谷氨酰胺、蛋氨酸、亮氨酸、肉贵酸钾、酪朊酸钠、维生素B2、维生素C/抗坏血酸、黄原胶、柠檬酸、瓜尔胶、聚丙烯酸钠
- 主营：酪蛋白酸钠、精氨酸、海藻酸钠、可可粉、抹茶粉、黄原胶、卡拉胶、维生素b、胍基乙酸、牛黄酸、双乙酸钠、大豆分离蛋白、苯丙氨酸、半胱氨酸、温轮胶、定优胶、文莱胶、明胶、木瓜蛋白酶、谷氨酰胺、甘氨酸、苏氨酸、谷氨酸、色氨酸
- 主营：木糖醇、乳糖、木糖、维生素CL-抗坏血酸、胍基乙酸、黄原胶、海藻酸钠、酪蛋白酸钠、酪蛋白/干酪素、甘氨酸、牛磺酸、瓜尔胶/瓜尔豆胶、果胶/苹果果胶、聚赖氨酸、苯丙氨酸、半胱氨酸、苯甲地那铵 苦精、蔗糖八乙酯 苦味剂、甘露糖醇/甘露醇、海藻糖、山梨糖醇/山梨醇、卡拉胶、蛋氨酸
- 主营：牌甘油、碳酸镁、牌饲料、牌菊粉、藻油粉、牌乳酸、叶绿素、蚯蚓肽、壳聚糖、牌磷脂、脑磷脂、牌脱氢、甲壳素、牌琼胶、牌果酸、牌肌酸、牌羟丙、氧化镁、精氨酸、牌酵母、牌果胶、牌糊精、大米肽、牌糖精、氨酸钠
- 主营：牌甘油、精氨酸、酪蛋白、抑甜粉、牌钴蓝、牌烟酸、牌饲料、牌酵母、刹口剂、风味酶、牌磷酸、牌乳酸、乳酸钙、牌果胶、牌乳糖、牌桔红、半乳糖、牌纽甜、牌橘黄、牡蛎肽、牌核糖、牌糊精、牌糖精、生物钙、干贝素
- 主营：水苏糖、牛磺酸、温轮胶、抑甜粉、魔芋胶、壳聚糖、干贝素、蛋白糖、甲壳素、香兰素、虾青素、苦味剂、鞣酸酶、鼠李糖、黄原胶、海藻酸钠、聚丙烯酸钠、木糖醇、酪蛋白酸钠、精氨酸、半胱氨酸、苯丙氨酸、亮氨酸、蛋氨酸、甘氨酸
- 主营：甘氨酸、水苏糖、除涩剂、鱼油粉、红曲黄、儿茶素、米糠素、甘露醇、硫酸锰、他拉胶、一水物、酪蛋白、磷酸氢、牛磺酸、褪黑素、碳酸镁、赖氨酸、纤维素、刹口剂、卡拉胶、泡多源、柚苷酶、乳糖酶、脯氨酸、筋力源
- 主营：营养强化剂、氨基酸、香精、生物素粉、酸度调节剂、甜味剂、增稠剂、防腐剂、抗氧化剂
- 主营：丙酸钙、肉桂酸、维生素C/抗坏血酸、edta二钠、抗氧剂dltp、纳他霉素、抗氧剂264、抗坏血酸、双乙酸钠、聚赖氨酸、胍基乙酸、抗氧剂t501、抗氧剂1010、半胱氨酸盐酸盐、半胱氨酸、果胶、干酪素、苯丙氨酸、乳酸链球菌素、肉桂酸钾、色氨酸、牛磺酸、低聚木糖、酪蛋白酸钠、维生素C、vc
- 主营：甘氨酸、水苏糖、韦兰胶、乳糖粉、五香粉、麦芽粉、海藻糖、增脆剂、甘露醇、水杨酸、硫酸锰、精氨酸、肌氨酸、酪蛋白、筋力源、牛磺酸、肉制品、温轮胶、赖氨酸、纤维素、茶氨酸、薄荷冰、泡多源、氯化锌、乳酸钠
- 主营：生物素1、三氯蔗糖、异麦芽酮糖醇