Overview
Benzyl Fluoride (C7H7F) is an organofluorine compound derived from toluene. It is a colorless to pale yellow liquid with a distinct aromatic odor. The compound is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. As a fluorinated derivative of toluene, Benzyl Fluoride exhibits unique reactivity due to the presence of the fluorine atom. This makes it valuable for introducing fluoromethyl groups into larger molecules, a common requirement in drug development and agrochemical production.
Physical and Chemical Properties
Benzyl Fluoride has a molecular weight of 110.13 g/mol and a density of 1.022 g/cm³ at 25°C. It is a volatile liquid with a boiling point of 139-140°C and a melting point of -35°C. The compound is soluble in common organic solvents like ethanol, ether, and acetone but has limited solubility in water. Chemically, Benzyl Fluoride is reactive towards strong oxidizing agents and can undergo nucleophilic substitution reactions. Its flammability requires careful handling, and it should be stored away from heat sources and open flames to prevent combustion hazards.
Main Applications
Benzyl Fluoride is widely used as a building block in organic synthesis, particularly in the pharmaceutical industry. It serves as a precursor for fluorinated compounds, which are increasingly important in drug design due to their enhanced metabolic stability and bioavailability. In addition to pharmaceuticals, Benzyl Fluoride finds applications in agrochemicals, specialty chemicals, and materials science. Its ability to introduce fluoromethyl groups makes it valuable for modifying the properties of polymers and other advanced materials.
Safety and Storage
Benzyl Fluoride is a flammable liquid and should be handled with appropriate precautions. Personal protective equipment (PPE), including gloves, goggles, and lab coats, is essential to prevent skin and eye contact. Inhalation of vapors should be avoided by working in a well-ventilated area or under a fume hood. Storage conditions should include a cool, dry place away from direct sunlight and heat sources. Containers must be tightly sealed to prevent evaporation and contamination. In case of spills, absorb with inert material and dispose of according to local regulations.
B2B Procurement Guide
When procuring Benzyl Fluoride, B2B buyers should prioritize suppliers who provide detailed technical specifications, including purity levels (typically 98% or higher) and CAS number verification. Requesting a Safety Data Sheet (SDS) is crucial for compliance and safe handling. Bulk purchases may offer cost advantages, but buyers should ensure proper storage facilities are available. Quality certifications (e.g., ISO, GMP) from suppliers can indicate reliability. Prices vary based on quantity and purity, with reference ranges commonly between $50-$150 per kg.
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