Overview
Flumequine is a synthetic antibacterial compound classified as a first-generation quinolone. Developed primarily for veterinary applications, it exhibits potent activity against a wide range of Gram-negative bacteria. The compound was first introduced in the 1970s and has since been used extensively in animal husbandry and aquaculture. As a chemical reagent, flumequine is typically supplied as a white crystalline powder with high purity grades suitable for research and pharmaceutical applications. Its mechanism of action involves inhibition of bacterial DNA gyrase, making it effective against various pathogenic microorganisms.
Physical and Chemical Properties
Flumequine presents as a stable, crystalline solid under normal conditions, with limited solubility in water but better solubility in alkaline media and organic solvents. The compound shows thermal stability up to its melting point of 253-255°C, beyond which decomposition occurs. The molecular structure features a fluorine atom at position 9 and a carboxylic acid group, both crucial for its antibacterial activity. Its UV absorption characteristics make it detectable at specific wavelengths, useful for analytical purposes. The pKa value of approximately 6.0 indicates its behavior as a weak acid in solution.
Main Applications
The primary application of flumequine is in veterinary medicine, particularly for treating bacterial infections in poultry, swine, and cattle. It's effective against Enterobacteriaceae, Pasteurella, and other pathogens causing respiratory and digestive system infections. In aquaculture, flumequine is used to control bacterial diseases in fish farming operations. The compound is administered through medicated feed or water treatments. Research applications include studies on bacterial resistance mechanisms and development of new quinolone derivatives.
Safety and Storage
Flumequine requires careful handling due to potential health effects. Personal protective equipment including gloves and safety glasses should be used when working with the powder form. Avoid creating dust and prevent inhalation exposure. Proper storage conditions include maintaining the reagent in tightly sealed containers at room temperature, protected from light and moisture. The compound should be kept separate from strong oxidizing agents. Shelf life typically exceeds two years when stored correctly.
B2B Procurement Guide
When sourcing flumequine for commercial or research purposes, buyers should prioritize suppliers who provide comprehensive analytical certificates (CoA) detailing purity (typically 98-99.5%) and impurity profiles. Bulk quantities (25kg drums) often offer better pricing for industrial applications. Regulatory compliance is essential - verify that the supplier meets relevant pharmacopeia standards (EP/USP) if the material is destined for pharmaceutical use. Consider lead times and minimum order quantities, as flumequine is sometimes produced in batch processes rather than being continuously available.
Related Manufacturers
- 主营：阿苯达唑原料、氟苯尼考原料、氨苄西林钠原料、氨苄西林原料、盐酸沃尼妙林
- 主营：磷铁粉、脱模剂、软化剂、氟甲喹、添加剂、增香剂、强还原剂、碳酸氢铵、氯化亚铁、改性涂料、研磨材料、成型助剂、磷酸三辛酯、触变润滑剂、高温防腐粉、高分子助剂、洗涤剂香精、生长调节剂、十六十八醇、染料中间体、乳液稳定剂、陶瓷着色剂、油漆稀释剂、表面活性剂、漆雾凝聚剂、硝化纤维稳定剂
- 主营：冲压油、苯酚cas、乙烯基、盐酸甲氟喹、底涂剂、cas71-41-0、cas95-50-1、4二碘苯、cas120-82-1、cas106-47-8、cas123-30-8、cas110-87-2、cas110-00-9、cas563-47-3、cas100-50-5、cas110-82-7、异构烷烃、甲基乙撑、白色粉末、丙撑二胺、板助焊剂、141b清洗剂、脱漆剂
- 主营：化工中间体、有机中间体、香精香料、日化原料、添加剂、表面活性剂、天然/合成树脂、分析试剂、催化剂、高分子材料
- 主营：4-D钠盐、N-甲基硫脲、N-甲基吡咯烷酮、氟甲喹厂家、单辛酸甘油酯、N-甲基邻氨基苯甲酸甲酯、三硫代碳酸钠、辛酸镁盐、菜籽油甲酯、8-辛二醇、羟丙基纤维素、硫酸烟酰苯胺、离子液体、咪唑、表面活性剂、光引发剂、紫外线吸收剂、UV单体
- 主营：杀菌剂、单宁酸、抗氧剂、日化原料、氟甲基磺、交联剂、咪唑钾、中间体、咪唑、绝缘材料、氧化钛铝、离子液体、苯基膦酸、2-吲哚甲酸、甲基咪唑啉、乳化稳定剂、油漆催干剂
- 主营：硫磺粉末
- 主营：金属催化剂
- 主营：膨胀剂、碳酸钙、降阻剂、氟甲喹生产厂家、环氧树脂、液体硅酸钠、水解蛋白粉、三氯异氰尿酸、速凝剂、水玻璃、硫酸铵、硫酸钡、纯碱、氯化钙、石灰、早强剂、甲酸钙
- 主营：中间体、香精香料、催化剂、有机原料、有机硅、表面活性剂
- 主营：化学品、香精香料、试剂、盐酸甲氟喹、中间体、有机硅、橡胶树脂、催化剂、纳米材料
- 主营：蛋白胨、多聚甲醛、螯合铁、盐酸甲氟喹、黄血盐钠、三氯乙烯、戊二醛、对苯二胺、异辛醇、甲醇、蛋氨酸、甲醇钠、乙氧基喹啉、硼酸、酵母浸膏、磷酸二氢钾、溶剂油、磷酸、苯酚、磁黄铁矿、正丁醇、黄丹粉、二甲基甲酰胺、四氢呋喃、甲基叔丁基醚
- 主营：羟基磷灰石、生物活性玻璃、布洛芬、全氟三丁胺、全氟三乙胺、全氟三丙胺、全氟聚醚、全氟萘烷、全氟己酮、溴壬烷、磷酸铵、甲乙基、褪黑素、嘧啶钠、莪术油、显色剂、叔丁醇、茜素红、乙氧基、异戊醇、脯氨酸、茚三酮、氯唑沙
- 主营：杀菌剂、硫酸铜、硫酸铵、氟化钠、二甲苯、航空煤油、氯乙酸、黄血盐钠、硫酸锌、二月桂酸二丁基锡、苯甲酸、乙二醇、叔丁醇、辛酸亚锡、己二酸二酰肼、二茂铁、多聚磷酸、多聚甲醛、乙醇、DMF、聚磷酸铵、甲醇、硝酸异辛酯、黄血盐钾
- 主营：己二酸二酰肼、2-甲基四氢噻吩-3-酮、3-甲基-2-丁硫醇、丙酸氯倍原料、三氟甲基磺酸铋、亚乙基硫脲、2-辛二醇、醋酸钯
- 主营：氟甲喹、溴代吡咯腈
- 主营：杀菌剂、小麦田除草剂、玉米田除草剂、封闭田除草剂、调节剂、杀虫剂、肥料、水溶肥、地下害虫颗粒剂、拌种剂、杀螨剂
- 主营：溴代吡咯腈、芥酸、异山梨醇、2,6-二氟苯胺、异山梨醇二甲醚、四氯苯醌、对氨基苯乙酸、四乙酰核糖、对氨基苯甲酸、蒽醌
- 主营：氟甲喹42835、分析纯试剂