Overview
Famotidine Intermediate is a critical chemical compound in the pharmaceutical industry, primarily used in the synthesis of Famotidine. Famotidine is a widely prescribed medication that functions as an H2 receptor antagonist, effectively reducing stomach acid production. The intermediate ensures the drug's efficacy and purity, making it a vital component in the manufacturing process. The quality of Famotidine Intermediate directly impacts the final drug product's performance. Pharmaceutical companies rely on high-purity intermediates to meet regulatory standards and ensure patient safety. The compound is synthesized under strict controlled conditions to maintain its integrity and effectiveness.
Physical and Chemical Properties
Famotidine Intermediate typically appears as a white to off-white crystalline powder. It is soluble in organic solvents such as methanol and ethanol but has limited solubility in water. The compound is known for its stability when stored under recommended conditions, which include a cool, dry environment away from direct sunlight and moisture. Key properties of Famotidine Intermediate include high purity and compatibility with pharmaceutical synthesis processes. These characteristics are essential for ensuring the intermediate's effectiveness in producing Famotidine. The compound's stability under controlled conditions makes it suitable for large-scale pharmaceutical manufacturing.
Main Applications
The primary application of Famotidine Intermediate is in the synthesis of Famotidine, a medication used to treat conditions related to excessive stomach acid production. Famotidine is commonly prescribed for ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. The intermediate plays a pivotal role in ensuring the drug's therapeutic efficacy. Beyond its use in Famotidine production, the intermediate may also find applications in research and development within the pharmaceutical industry. Its high purity and stability make it a valuable component for developing new formulations or improving existing ones. However, its primary use remains in the manufacturing of Famotidine.
Safety and Storage
Handling Famotidine Intermediate requires adherence to safety protocols to minimize risks. Personal protective equipment (PPE), including gloves and goggles, should be worn to prevent skin contact or inhalation. The compound should be stored in a cool, dry place, away from direct sunlight and moisture, to maintain its stability and shelf life. Proper storage conditions are crucial for preserving the intermediate's quality. Exposure to unfavorable conditions may degrade the compound, affecting its efficacy in pharmaceutical synthesis. Additionally, disposal should comply with local regulations to prevent environmental contamination.
B2B Procurement Guide
When procuring Famotidine Intermediate, it is essential to source from suppliers who comply with Good Manufacturing Practices (GMP). Certificates of analysis (CoA) should be provided to verify the compound's purity and quality. The reference price range is approximately $50-$200 per kilogram, depending on purity and supplier reliability. Buyers should also consider the supplier's reputation, delivery timelines, and ability to meet large-scale demands. Establishing long-term relationships with trusted suppliers can ensure a consistent supply of high-quality intermediates. Additionally, buyers should stay informed about regulatory changes that may impact procurement processes.
Related Manufacturers
- 主营：偏钒酸钠、还原铁粉、次磷酸钠、金属有机物、二水氯化铜、对二氯苄、次磷酸、黄血盐钾、黄血盐钠、氟化钾、氟化钠、红丹粉、黄丹粉、硫氰酸钠、硫氰酸钾、乙二胺四乙酸二钾
- 主营：黄血盐钾、黄血盐钠、氟化钾、氟化钠、氟硅酸铵、水杨酸钠、聚六亚甲基胍盐酸盐、黄丹粉、九水硫化钠、红丹粉、氢氧化钡、氧化铋、对甲苯磺酸、二氧化硒、三硫代碳酸钠、醋酸铅、氯化铅、还原铁粉、碱式碳酸铅、次磷酸、对二氯苄
- 主营：杀菌剂、7784-22-7、巴豆酸、稀释剂、酒石酸、维生素、蒸煮剂、除草剂、润滑油、除锈剂、白糊精、聚氯乙烯、多肽合成、作为染料、作防腐剂、苯甲羟肟、酚醛树脂、光学玻璃、作聚合终止、空调除湿剂、丙烯酸乙酯、热固性塑料、黄色发光剂
- 主营：乙酸铵、阻燃剂、己二酸、用作法莫替丁的中间体、电容器、钼酸铵、磷酸一铵、氢氧化铝、聚合催化剂、表面活性剂、三氧化二锑、工业清洗剂、纸的柔软剂、氮磷复合肥料、粉末涂料固化剂、食品高级发酵剂
- 主营：氟化铝、发酵粉、缓冲液、用作法莫替丁的中间体、钼酸铵、分析试剂、研究试剂、碳酸氢铵、磷酸一铵、防水织物、聚丙烯酰胺、聚合催化剂、三氧化二锑、对甲苯磺酸、纸的柔软剂、氮磷复合肥料、粉末涂料固化剂、对三氟甲基苯腈
- 主营：硫酸钐、对甲苯磺酸、黄血盐钠、法莫替丁中间体、对苯二酚、巯基乙酸、一氧化铅、氢氧化钡、过氧化苯甲酰、醋酸铅、磷酸三丁酯、卡松、磷酸氢二钠、丙酮肟、水杨酸钠、硫氰酸钠、八水氢氧化锶、无水氟化钾、磷酸锌、磷酸脲、硫化钡
- 主营：甘氨酸、阻燃剂、胶黏剂、蒽甲酸、热熔胶、退除剂、嘧菌酯、中性红、3282-24-4、肉桂醛、退镍液、乙氧基、增弹剂、环氧胶、2768-02-7、阻燃毯、7377-08-4、4865-84-3、亮氨酸、抛光盐、5471-63-6、甲基橙、戊二酸、4355-11-7、插入管