Overview
Evodiamine is a bioactive alkaloid derived from the fruit of Evodia rutaecarpa, a plant commonly used in traditional Chinese medicine. It is known for its pharmacological properties, including anti-inflammatory, analgesic, and anti-obesity effects. The compound has garnered interest in both pharmaceutical research and nutraceutical applications due to its potential health benefits. Evodiamine's molecular structure allows it to interact with various biological pathways, making it a subject of ongoing scientific studies. Its use dates back centuries in herbal remedies, particularly in East Asia, where it is valued for its therapeutic properties.
Physical and Chemical Properties
Evodiamine appears as a yellowish crystalline powder with a melting point range of 278-280°C. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) but has limited solubility in water. The compound's molecular weight is 303.36 g/mol, and its stability is influenced by storage conditions, requiring protection from light and moisture. The alkaloid's chemical structure includes a quinazoline core, which contributes to its bioactive properties. Its stability and solubility profile make it suitable for formulation in various pharmaceutical and supplement products, though careful handling is required to maintain its integrity.
Main Applications
Evodiamine is primarily used in traditional Chinese medicine to treat conditions such as gastrointestinal disorders, headaches, and hypertension. Modern research explores its potential in weight management, pain relief, and anti-cancer therapies. It is also incorporated into dietary supplements for its metabolic and anti-inflammatory benefits. In the pharmaceutical industry, evodiamine is studied for its ability to modulate TRPV1 channels, which are involved in pain perception. Its dual role as a therapeutic agent and a research tool underscores its versatility in both clinical and laboratory settings.
Safety and Storage
Evodiamine should be stored in a cool, dry environment, protected from light and moisture to prevent degradation. Proper handling includes the use of gloves and protective eyewear to avoid skin and eye irritation. The compound is generally considered safe at therapeutic doses but may cause adverse effects if misused. Regulatory guidelines vary by region, so it is essential to comply with local safety standards when handling or distributing evodiamine. Suppliers should provide material safety data sheets (MSDS) to ensure safe usage in industrial and research applications.
B2B Procurement Guide
When procuring evodiamine, prioritize suppliers with verified certifications such as ISO or GMP to ensure product quality. Request certificates of analysis (CoA) to confirm purity levels, which typically range from 95% to 99%. Bulk purchases may reduce costs, but negotiate terms to balance price and quality. Consider logistical factors such as shipping conditions and lead times, especially for international orders. Establish long-term relationships with reliable suppliers to secure consistent quality and competitive pricing. Transparency in sourcing and compliance with regulatory requirements is critical for B2B transactions.
Related Manufacturers
- 主营：藤茶提取物、枳椇子提取物、二氢槲皮素、吴茱萸内酯、槲皮素、地龙蛋白肽、马齿苋提取物、甘草提取物、黄芪粉、罗汉果粉、鱼腥草提取物、淡竹叶提取物、竹叶黄酮、葛根提取物、玉米低聚肽、酸枣仁提取物、荷叶提取物、人参提取物、蒲公英提取物、益智仁提取物、桑叶提取物、阿胶粉、麦芽提取物
- 主营：吴茱萸内酯、对照品、标准品
- 主营：苦参碱母液、黑米花青素、白芍提取物芍药苷、黄柏内酯、苦参提取物、枸杞提取物、侧柏叶提取物
- 主营：苦参碱、氧化苦参碱、七叶皂苷钠、吴茱萸碱、吴茱萸次碱、七叶皂苷、黑米花色苷、鬼臼树脂、鬼臼毒素、黑米花青素、龙胆苦苷、青蒿琥酯、青蒿素、博落回总碱、鱼藤酮、二苯乙烯苷、丝肽粉、人参皂甙
- 主营：中药标准品、标准品对照品、天然化合物、吴茱萸内酯、标准品、分析试剂、细胞实验、动物实验、中药提取物、单体化合物、科研实验用
- 主营：对照品、标准品、三叶苷、吴茱萸、姜烯酚、人参皂苷、地黄苷、科研试剂、实验室自制、生育三烯酚
- 主营：甲基原、钩藤碱、络塞定、吴茱萸、丹皮酚、2086-83-1、6836-11-9、鞣花酸、川楝素、黄芩素、苍术素、松脂素、管花苷、熊果酸、苦参碱、6926-08-5、土莫酸、苜蓿素、茯苓酸、柚皮素、3668-14-2、白麻苷、秦皮苷、葛花苷、山奈酚、柚皮苷
- 主营：钩藤碱、丹皮酚、c17h26o10、吴茱萸内酯、高良姜、丹参酮、鞣花酸、川楝素、苍术素、芦竹碱、管花苷、苦参碱、土贝母、柚皮素、白麻苷、甜菜碱、紫草素、络石苷、木皂苷、苏木素、甘露糖、番茄碱、青蒿酸、皂苷rg2、芹菜素、紫杉醇
- 主营：马齿苋酰胺O、丹参酮、马齿苋酰胺N、银杏内酯C、岩大戟内酯A、银杏内酯A、17-羟基岩大戟内酯、岩大戟内酯B、银杏内酯B、马齿苋酰胺B、阿魏酸、人参皂苷 RH3、人参皂苷RB2、人参皂苷 Rf、20(S)-人参皂苷、桑根酮C、橙皮苷、桑根酮D、茶多酚、丹酚酸c、阿奇霉素、人参皂苷 F1、马齿苋酰胺A
- 主营：锁阳提取物、栀子苷、藏红花素、吴茱萸、西红花苷、二苯乙烯苷、山奈酚、花椒油树脂、丹酚酸B、丹参素、丹参酮IIA、虫草素、葛根素、三七皂甙、柚皮苷、连翘苷、肉苁蓉苷、黄腐酚、积雪草苷、植物醇、茶多酚、EGCG、芍药甙、神经酰胺、植物鞘胺醇、天麻提取物天麻素
- 主营：锁阳提取物、荷叶提取物、黄芩提取物、吴茱萸内酯、黄芪提取物、红参提取物、枸杞提取物、蒲公英提取物、马齿苋提取物、鱼腥草提取物、皂角提取物、透骨草提取物、菊花提取物、黄柏提取物、饲料添加剂、食品添加剂、植物提取物、黄连提取物、固体饮料、果汁粉粉、栀子苷10%~30%
- 主营：标准品、中药对照品、槲皮万寿菊素、吴茱萸内酯、新绿原酸
- 主营：药品检测标准品、药物杂质标准品、对照品、吴茱萸、中药对照药材、中药农残空白基质、分析标准品、仪器检测校准品、金属离子标准溶液、滴定溶液、食品检测标准物质、有机检测标准溶液、指示液、缓冲液、电导率溶液、PH标准溶液、熔点标准品、国家标准物质、比色液
- 主营：砷酸锂、白云石、水合物、吴茱萸、氮化锌、144205-68-5、二叔丁基、利多卡因、碳化钨钴、泛影葡胺、化合物库、1093222-27-5、羟基苯基、八钼酸铵、生化试剂、苯甲酸乙酯、熊去氧胆酸、胆酸二水合、乙酰丙酮锌、湿法云母粉、六氟磷酸盐、干法云母粉、苯碳酸甲酯、脱氧胆酸二水、氨基二琥珀酸、对乙酰氨基苯酚
- 主营：对照品、科研实验、试剂盒、吴茱萸内酯、多糖、安石榴苷、儿茶素、绿原酸、尿石素、人参皂苷、花青素、维生素、异鼠李素、甘草系列、人参系列、补骨脂系列、雷公藤系列、黄芩系列、柴胡系列、丹参系列、酸枣仁系列、重楼系列、大黄系列、五味子系列、化合物、黄芪皂苷系列