Overview
Ethyl hippurate, also known as ethyl 2-benzamidoacetate, is an ester derived from hippuric acid. It is commonly used as an intermediate in pharmaceutical synthesis and organic chemistry research. The compound is characterized by its white crystalline appearance and stability under standard conditions. Ethyl hippurate is synthesized through the esterification of hippuric acid with ethanol. Its molecular structure includes a benzamido group, which contributes to its reactivity in various chemical reactions. This compound is primarily utilized in laboratories and industrial settings for specialized applications.
Physical and Chemical Properties
Ethyl hippurate is a white to off-white crystalline powder with a molecular weight of 207.23 g/mol. It has a melting point of approximately 70-72°C and is soluble in organic solvents such as ethanol and ether. The compound exhibits slight solubility in water, making it suitable for specific reaction conditions. The stability of ethyl hippurate under normal storage conditions ensures its utility in long-term applications. Its ester group makes it a versatile intermediate for further chemical modifications. Key properties include its reactivity with nucleophiles and its role in peptide synthesis.
Main Applications
Ethyl hippurate is widely used as an intermediate in the synthesis of pharmaceuticals and bioactive compounds. It serves as a building block for more complex molecules, particularly in peptide and amide chemistry. Researchers value it for its predictable reactivity and ease of handling. In addition to pharmaceutical applications, ethyl hippurate is employed in organic synthesis for creating specialty chemicals. Its role in academic and industrial research underscores its importance in advancing chemical knowledge and developing new materials.
Safety and Storage
Handling ethyl hippurate requires adherence to standard laboratory safety protocols. Avoid inhalation, ingestion, or direct skin contact by using appropriate personal protective equipment (PPE) such as gloves and goggles. In case of exposure, rinse affected areas thoroughly with water. Store the compound in a cool, dry place away from light and moisture to maintain its stability. Proper labeling and secure containers are essential to prevent accidental misuse or contamination. Always follow local regulations for chemical storage and disposal.
B2B Procurement Guide
When procuring ethyl hippurate, prioritize suppliers with a proven track record of quality and consistency. Verify the CAS number (5202-88-4) and request certificates of analysis to ensure purity and authenticity. Bulk purchases may offer cost advantages, but ensure storage capacity aligns with usage rates. Consider logistical factors such as shipping conditions and lead times to maintain supply chain efficiency. Establish clear communication with suppliers regarding specifications, packaging, and handling requirements to avoid discrepancies and ensure smooth transactions.
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