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Ethyl Chloride

Updated: 2026-07-20

Overview

Chloroethane, commonly known as ethyl chloride, is a halogenated hydrocarbon with the chemical formula C2H5Cl. It exists as a colorless gas or volatile liquid at room temperature and has a sweet, ethereal odor. Historically, it was widely used as a refrigerant and in the production of tetraethyl lead, a gasoline additive. Today, its applications span industrial and medical fields, including use as a solvent and topical anesthetic. Chloroethane is synthesized through the reaction of ethanol with hydrogen chloride or by the chlorination of ethane. Its volatility and flammability necessitate careful handling and storage. Despite its declining use in some applications due to environmental concerns, chloroethane remains relevant in specialized industrial processes and medical practices.

Physical and Chemical Properties

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Chloroethane is a highly volatile compound with a boiling point of 12.3 °C and a melting point of -138.7 °C. Its density is approximately 0.92 g/cm³ in liquid form at its boiling point. The compound is slightly soluble in water but mixes readily with most organic solvents, including ethanol and diethyl ether. Chemically, chloroethane is relatively stable under normal conditions but can decompose under extreme heat or in the presence of strong bases, releasing toxic hydrogen chloride gas. Its flammability makes it a significant fire hazard, requiring precautions such as storage in flame-proof containers and use in well-ventilated areas.

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Main Applications

Chloroethane's primary industrial use is as a solvent in the production of ethyl cellulose and other chemicals. It also serves as a refrigerant in low-temperature applications. In the past, it was a key component in the manufacture of tetraethyl lead, an anti-knock additive for gasoline, though this use has largely been phased out due to environmental regulations. In the medical field, chloroethane is used as a topical anesthetic due to its rapid evaporation, which cools the skin and numbs the area. It is also employed in dermatology for minor surgical procedures and wart removal. Additionally, it finds use in the synthesis of pharmaceuticals and agrochemicals.

Safety and Storage

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Chloroethane is highly flammable and poses significant fire and explosion risks. It should be stored in tightly sealed containers in a cool, well-ventilated area away from heat sources and open flames. Proper grounding and bonding are essential to prevent static discharge during handling. Exposure to chloroethane can cause dizziness, nausea, and respiratory irritation. Prolonged or high-level exposure may lead to central nervous system depression. Personal protective equipment, including gloves and goggles, is recommended when handling the compound. In case of spills, evacuate the area and use appropriate absorbents to contain the liquid.

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B2B Procurement Guide

When procuring chloroethane, buyers should prioritize suppliers who provide certificates of analysis (CoA) to verify purity and composition. Industrial-grade chloroethane typically has a purity of 99% or higher, while medical-grade variants may have additional specifications. Bulk purchases often offer cost advantages, but storage capacity and safety measures must be considered. Transportation regulations for hazardous chemicals apply, so ensure compliance with local and international standards. Buyers should also evaluate suppliers based on reliability, delivery timelines, and after-sales support.

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