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Ethyl 1-hydroxycyclohexanecarboxylate

Updated: 2026-08-04

Overview

Ethyl 1-hydroxy-1-cyclohexanecarboxylate is an organic compound primarily used as an intermediate in pharmaceutical and chemical synthesis. Its molecular structure includes an ester group and a hydroxyl group, making it versatile for various reactions. This compound is typically synthesized through esterification processes involving cyclohexanecarboxylic acid derivatives. Its applications span across industries requiring fine chemicals, particularly in drug development and specialty chemical manufacturing.

Physical and Chemical Properties

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Ethyl 1-hydroxy-1-cyclohexanecarboxylate is a colorless to pale yellow liquid at room temperature. It is soluble in common organic solvents like ethanol, ether, and acetone but has limited solubility in water. The compound's ester and hydroxyl functional groups contribute to its reactivity, enabling its use in nucleophilic substitution and condensation reactions. Stability under normal storage conditions makes it suitable for industrial use, though exposure to strong acids or bases should be avoided.

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Main Applications

This chemical is predominantly utilized in the pharmaceutical industry as a building block for active pharmaceutical ingredients (APIs). Its structure allows for further functionalization, making it valuable in synthesizing complex molecules. Additionally, it serves as an intermediate in agrochemicals and specialty chemicals. Research laboratories may also employ it for developing novel organic compounds with potential industrial applications.

Safety and Storage

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Ethyl 1-hydroxy-1-cyclohexanecarboxylate requires careful handling due to potential skin and eye irritation. Personal protective equipment (PPE) such as gloves and goggles is recommended during use. Storage should be in tightly sealed containers, placed in a cool, dry, and well-ventilated area. Incompatible materials include strong oxidizing agents and bases. Spills should be contained and cleaned promptly using appropriate absorbents.

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B2B Procurement Guide

When sourcing this compound, verify supplier credentials and request certificates of analysis (COA) to ensure purity and quality. Bulk purchases may offer cost advantages, but storage capacity and shelf life should be considered. Reliable suppliers often provide technical support and safety data sheets (SDS). Establish long-term partnerships with manufacturers to secure consistent supply and favorable terms. Prices vary based on order volume and market conditions.

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