Overview
Emodin reference standard is a high-purity anthraquinone derivative isolated from plants such as Rheum palmatum and Polygonum cuspidatum. It is widely used as a standard in pharmaceutical and biochemical research due to its well-characterized properties. As a reference material, emodin ensures the accuracy and reproducibility of analytical methods like HPLC and UV spectrophotometry. Its role in quality control is critical for herbal medicine formulations and drug development.
Physical and Chemical Properties
Emodin is an orange to yellow crystalline powder with a molecular weight of 270.24 g/mol. It has a melting point of 256-257°C and is soluble in organic solvents like ethanol and DMSO but only slightly soluble in water. The compound exhibits strong UV absorption, making it suitable for spectrophotometric analysis. Its stability under controlled storage conditions (2-8°C, protected from light and moisture) ensures long-term usability in laboratory settings.
Main Applications
Emodin reference standard is primarily used in pharmaceutical quality control to validate the potency and purity of herbal extracts and formulations. It serves as a biomarker for plants like rhubarb and Polygonum species. In research, emodin is studied for its potential pharmacological effects, including anti-inflammatory, anticancer, and antimicrobial properties. Analytical labs rely on it for method development and calibration in HPLC, TLC, and other chromatographic techniques.
Safety and Storage
Emodin should be handled with care to avoid exposure. Use gloves, goggles, and lab coats when working with the compound. Inhalation or ingestion can cause irritation, and proper ventilation is recommended. For long-term stability, store emodin in a tightly sealed container under refrigerated conditions (2-8°C). Protect from light and moisture to prevent degradation. Dispose of waste according to local hazardous material regulations.
B2B Procurement Guide
When procuring emodin reference standard, prioritize suppliers with ISO certification or GMP compliance. Request certificates of analysis (CoA) to verify purity (typically >98%) and check for batch-to-batch consistency. Compare pricing from multiple vendors, but avoid compromising quality for cost. Bulk purchases may offer discounts, but ensure proper storage capacity. Reliable suppliers often provide technical support and documentation for regulatory compliance.
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