Overview
Emodin extract is a bioactive anthraquinone compound naturally found in plants such as rhubarb (Rheum palmatum), Polygonum cuspidatum, and Aloe vera. It has been used in traditional Chinese medicine for centuries due to its laxative and anti-inflammatory properties. Modern research highlights its potential in treating conditions like cancer, diabetes, and microbial infections. Its versatility makes it valuable in pharmaceuticals, nutraceuticals, and cosmetic formulations. The extract is typically obtained through solvent extraction or chromatographic purification to achieve high purity levels.
Physical and Chemical Properties
Emodin appears as an orange-yellow crystalline powder with a molecular weight of 270.24 g/mol. It is stable under normal conditions but degrades when exposed to prolonged light or high temperatures. The compound is soluble in organic solvents like ethanol and methanol but poorly soluble in water. Its solubility increases in alkaline solutions due to the formation of soluble salts. Key chemical properties include its ability to chelate metals and act as a redox-active molecule, contributing to its antioxidant effects.
Main Applications
In pharmaceuticals, emodin is studied for its anticancer effects, particularly in inhibiting tumor growth and metastasis. It also shows promise in managing inflammatory diseases like arthritis and colitis. The cosmetic industry utilizes emodin for its antioxidant and skin-brightening properties. It is incorporated into anti-aging creams and serums. Additionally, emodin is used in research laboratories as a reference standard for studying anthraquinone metabolism and bioactivity.
Safety and Storage
Emodin requires careful handling due to its potential to cause skin and eye irritation. Laboratory personnel should use gloves and goggles when working with the compound. Storage conditions are critical to maintaining stability. Emodin should be kept in airtight containers, protected from light and moisture, at temperatures below 25°C. Long-term storage may require refrigeration. Bulk quantities should be labeled with hazard warnings and handled according to GHS guidelines.
B2B Procurement Guide
When sourcing emodin extract, prioritize suppliers who provide certificates of analysis (CoA) detailing purity (typically 95-98% by HPLC), residual solvents, and heavy metal content. Reputable suppliers often comply with USP or EP monographs. Consider ordering small batches for quality testing before large-scale procurement. Pricing varies based on purity and volume; bulk purchases (kilograms) may reduce costs by 10-20%. Ensure the supplier offers proper documentation for international shipping, including MSDS and customs declarations.
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