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EDTA Disodium

Updated: 2026-07-15

Overview

EDTA Disodium is a sodium salt of ethylenediaminetetraacetic acid (EDTA), renowned for its exceptional ability to chelate metal ions. It forms stable complexes with divalent and trivalent metals like calcium, magnesium, and iron, making it indispensable in industries requiring metal ion control. Its versatility spans food preservation, cosmetics, pharmaceuticals, and water treatment. First synthesized in the 1930s, EDTA Disodium’s chelation properties were quickly harnessed for industrial use. Today, it is manufactured under strict quality standards to ensure consistency in applications ranging from stabilizing beverages to enhancing drug formulations.

Physical and Chemical Properties

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EDTA Disodium appears as a white, odorless crystalline powder with high water solubility. Its molecular structure features four carboxylate groups and two amine nitrogens, enabling it to bind metal ions in a hexadentate manner. This results in highly stable, water-soluble complexes. The compound decomposes at 248°C without boiling. Its chelation efficiency is pH-dependent, peaking in alkaline conditions. Unlike EDTA free acid, the disodium salt is easier to handle due to its solubility and neutral pH in solution.

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Main Applications

In food and beverages, EDTA Disodium prevents oxidation by sequestering metal catalysts, extending shelf life. It is approved as a preservative (E386) in limited concentrations. Cosmetics utilize it to stabilize formulations by neutralizing metal impurities in ingredients like surfactants and dyes. Water treatment plants employ it to inhibit scale formation in boilers and pipelines. In pharmaceuticals, it acts as an anticoagulant in blood collection tubes and a detoxifier for heavy metal poisoning. Laboratories use it as a buffer and complexometric titrant.

Safety and Storage

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While not highly toxic, prolonged exposure to EDTA Disodium dust may irritate the respiratory tract and skin. Use gloves and masks during handling. It is biodegradable but can mobilize heavy metals in the environment, requiring careful disposal. Store in original containers away from moisture and incompatible materials (e.g., strong oxidizers). Shelf life typically exceeds two years when stored properly. Regulatory limits apply in food and cosmetic applications, requiring compliance with local standards (e.g., FDA, EU).

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B2B Procurement Guide

Bulk buyers should prioritize suppliers with ISO 9001 or GMP certifications to ensure quality consistency. Key specifications include purity (≥99%), heavy metal content (<10 ppm), and chloride/sulfate limits. Packaging options include 25kg bags or 1-ton drums with moisture barriers. Request batch analysis certificates and SDS documentation. For niche applications (e.g., pharmaceuticals), opt for USP/EP-grade material. Spot prices fluctuate with raw material (ethylene diamine) costs; long-term contracts may offer stability. China and India are major producers, but verify export compliance.

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