Overview
Dried toad, or 'Gan Chan Chu,' is a traditional Chinese medicinal product made by dehydrating whole toads (typically Bufo bufo gargarizans or Bufo melanostictus). It has been used for centuries in East Asian folk medicine for its purported therapeutic effects, particularly in treating heart conditions and tumors. In modern contexts, dried toad is studied for its bioactive compounds, such as bufadienolides, which exhibit cardiotonic and potential anticancer properties. The product is available in whole, sliced, or powdered forms, often processed under strict hygienic conditions to preserve its medicinal value.
Physical and Chemical Properties
Dried toad appears as a dark brown, brittle material with a distinctive earthy odor. Its bioactive components, including bufadienolides and serotonin analogs, are heat-stable but degrade under prolonged exposure to moisture or UV light. Solubility varies by compound: bufadienolides are partially soluble in alcohol, while proteins and peptides may dissolve in water. The product is typically free from synthetic additives, though adulteration with fillers is a known issue in lower-quality batches.
Main Applications
In traditional Chinese medicine (TCM), dried toad is prescribed for detoxification, pain relief, and to stimulate circulation. It is often combined with other herbs in formulas like 'Liu Shen Wan' for throat infections. Pharmaceutical research focuses on isolating bufadienolides for potential anticancer drugs, such as cinobufagin. B2B buyers include TCM manufacturers, research institutions, and cosmetic companies exploring its anti-inflammatory properties.
Safety and Storage
Dried toad contains toxic compounds (e.g., bufotoxin) and must be processed or prescribed by trained practitioners. Improper use can cause severe poisoning, with symptoms like arrhythmia or vomiting. Storage requires airtight containers in cool (below 25°C), dry conditions to prevent mold or compound degradation. Suppliers should provide certificates of analysis (CoA) confirming heavy metal and microbial safety.
B2B Procurement Guide
When sourcing dried toad, prioritize suppliers compliant with Good Agricultural and Collection Practices (GACP). Key due diligence includes verifying CITES permits (for wild-sourced toads) and HPLC test reports for bioactive compound content. Pricing varies by origin and processing method: wild-caught toads command higher prices but face sustainability concerns. Consider farmed alternatives or lab-tested extracts for consistent quality. MOQs typically start at 5 kg for wholesale transactions.
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