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Dodecyl gallate

Updated: 2026-08-05

Overview

Dodecyl gallate is an ester derived from gallic acid and dodecanol, primarily used as an antioxidant in various industries. Its chemical stability and ability to prevent oxidation make it valuable in preserving fats, oils, and other perishable substances. The compound is synthesized through esterification, ensuring high purity for industrial applications. In the food industry, dodecyl gallate is classified as a food additive (E312 in the EU) and is commonly used to extend shelf life. Its effectiveness in low concentrations makes it a cost-effective choice for manufacturers. Beyond food, it finds applications in cosmetics and pharmaceuticals, where oxidative stability is critical.

Physical and Chemical Properties

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Dodecyl gallate appears as a white to off-white crystalline powder with a melting point of 95-98°C. Its molecular weight is 338.44 g/mol, and it is characterized by the presence of a gallate group attached to a dodecyl chain. This structure contributes to its lipophilic nature, making it soluble in organic solvents like ethanol and acetone but only slightly soluble in water. The compound's antioxidant properties stem from its ability to donate hydrogen atoms, neutralizing free radicals that cause oxidation. It is stable under normal storage conditions but may degrade when exposed to prolonged heat or UV light. These properties dictate its handling and storage requirements in industrial settings.

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Main Applications

Dodecyl gallate is widely used as an antioxidant in the food industry, particularly in products containing fats and oils, such as baked goods, snacks, and processed meats. It prevents rancidity and maintains product quality during storage. In cosmetics, it stabilizes formulations like creams and lotions, protecting them from oxidative degradation. The pharmaceutical industry employs dodecyl gallate in drug formulations to enhance stability, especially in lipid-based delivery systems. Additionally, it serves as an additive in industrial lubricants and plastics to inhibit oxidation and prolong material lifespan. Its versatility across sectors underscores its importance in B2B supply chains.

Safety and Storage

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Dodecyl gallate is generally regarded as safe when used within regulatory limits, but improper handling can cause skin or eye irritation. Workers should wear gloves and goggles when handling the powder. Ingestion or inhalation of large quantities may require medical attention, making proper ventilation essential in industrial environments. Storage conditions are critical to maintaining the compound's efficacy. It should be kept in a cool, dry place, sealed in airtight containers to prevent moisture absorption. Prolonged exposure to light or high temperatures can degrade its antioxidant properties, reducing its effectiveness in applications.

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B2B Procurement Guide

When procuring dodecyl gallate, B2B buyers should prioritize suppliers who provide certificates of analysis (CoA) to verify purity (typically >98%). Compliance with international standards like FDA 21 CFR or EU regulations is essential for food and pharmaceutical applications. Buyers should also assess the supplier's packaging options to ensure product integrity during transit. Price fluctuations may occur based on raw material availability and demand. Bulk purchases (e.g., 25 kg drums) often reduce costs but require adequate storage facilities. Buyers are advised to request samples for quality testing before large-scale orders and to establish long-term contracts with reliable suppliers to secure stable pricing.

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