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Dodecanenitrile

Updated: 2026-07-15

Overview

Dodecanenitrile, commonly referred to as lauronitrile, is an organic nitrile compound primarily used as an intermediate in chemical synthesis. It is a versatile chemical with applications spanning multiple industries, including fragrances, pharmaceuticals, and agrochemicals. Its molecular structure, consisting of a 12-carbon chain with a nitrile functional group, makes it valuable for producing derivatives like fatty amines and carboxylic acids. Dodecanenitrile is synthesized through the reaction of dodecyl bromide with sodium cyanide or via the hydrocyanation of undecene. The compound's stability and reactivity under controlled conditions make it a preferred choice for industrial applications requiring nitrile intermediates.

Physical and Chemical Properties

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Dodecanenitrile is a clear, colorless to pale yellow liquid with a mild odor. It has a density of approximately 0.82 g/cm³ at 20°C and a boiling point ranging between 252-254°C. The compound is insoluble in water but dissolves readily in organic solvents such as ethanol, ether, and chloroform. Chemically, dodecanenitrile is stable under normal conditions but can react with strong oxidizing agents, acids, and bases. Its nitrile group (-C≡N) is highly reactive, enabling transformations into other functional groups like amines or carboxylic acids through hydrolysis or reduction reactions.

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Main Applications

Dodecanenitrile serves as a key intermediate in the synthesis of various chemicals. In the fragrance industry, it is used to produce musk-like scents and other odorants. The pharmaceutical sector utilizes it to create active ingredients and drug precursors. Additionally, dodecanenitrile finds use in agrochemical production, particularly in formulating pesticides and herbicides. Its ability to act as a precursor for fatty amines and surfactants also makes it valuable in the manufacture of detergents and corrosion inhibitors.

Safety and Storage

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Dodecanenitrile is classified as a flammable liquid and should be handled with care. Proper storage involves keeping it in a cool, dry, well-ventilated area away from heat sources and oxidizing agents. Containers must be tightly sealed to prevent moisture absorption and evaporation. Safety precautions include wearing gloves, goggles, and respiratory protection when handling the compound. In case of spills, absorb with inert material and dispose of according to local regulations. First aid measures for exposure include rinsing skin or eyes with water and seeking medical attention if ingested or inhaled.

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B2B Procurement Guide

When procuring dodecanenitrile, verify the supplier's credibility and request documentation such as the material safety data sheet (MSDS) and certificate of analysis (CoA). Key specifications to check include purity (typically 98-99%), CAS number (2437-25-4), and absence of impurities. Bulk purchases may qualify for discounts, but ensure proper storage facilities are available. Consider suppliers who offer technical support and can provide customized packaging options. Prices vary based on quantity and purity, with reference ranges commonly between $50-$100 per kilogram.

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