Diphenylphosphine
Overview
Diphenylphosphine (DPPH) is a versatile organophosphorus compound primarily employed as a ligand in transition metal catalysis. Its electron-donating properties make it valuable in cross-coupling reactions and asymmetric synthesis. Industrially, it serves as a precursor for phosphine-based flame retardants and agrochemicals. Due to its air sensitivity, commercial DPPH is typically stabilized under nitrogen or argon to prevent oxidation.
Physical and Chemical Properties
DPPH is a low-viscosity liquid with a pungent odor, degrading upon prolonged air exposure to form diphenylphosphine oxide. Its reducing ability stems from the reactive P-H bond, which participates in nucleophilic additions. Thermal stability up to 280°C allows its use in high-temperature processes. The compound’s solubility in nonpolar solvents like toluene facilitates its integration into organic reaction systems.
Main Applications
In catalysis, DPPH modifies metal centers in palladium and nickel complexes for C-C bond formations (e.g., Suzuki couplings). Pharmaceutical manufacturers utilize it to synthesize chiral phosphine ligands. Other uses include modifying polymer properties and producing flame retardants. Its derivatives are explored in OLED materials due to their electron-transport characteristics.
Safety and Storage
DPPH requires strict handling under inert conditions to prevent fires or toxic fumes. Storage in amber glass bottles with PTFE-lined caps is recommended. Leak-proof containers and grounding are essential during transfer. Exposure controls: Use fume hoods, nitrile gloves, and respiratory protection. Spills should be neutralized with inert absorbents and disposed as hazardous waste.
B2B Procurement Guide
Industrial buyers should prioritize suppliers offering batch analysis certificates (e.g., GC purity reports). Bulk shipments often use steel drums with nitrogen blankets for stability. Key due diligence points: Check REACH/SDS compliance, lead times (typically 2–4 weeks), and supplier track record in handling air-sensitive chemicals. Sample testing is advised for new vendors.
Related Manufacturers
- 主营：石蜡油、氯化石蜡、乙酰乙酸甲酯、十二烷基苯磺酸、香精、柔顺剂、表面活性剂
- 主营：碳酸钾、氨水、液碱、精己二酸、对苯二甲酸、二甲基甲酰胺、二甲苯、乙二醇、二乙二醇、对苯二甲酸二甲酯、磷酸二氢钾、醋酸、甲醇、醋酸乙酯、柠檬酸、聚丙烯酰胺、氯化钠
- 主营：增塑剂、草酸镍、阻燃剂、1-二十烯、磷酸三钾、丙二醇甲醚、栀子蓝、抗氧剂、偶联剂、异壬酸、间氟溴苄、异胞嘧啶、油墨油剂、洗涤助剂、苯磺酸钠、单体香料、环磺酮酸、分散染料、无机颜料、苹果酸镁、表面处理剂、化妆品原料、丁酸甘油酯、硅烷处理剂、表面活性剂
- 主营：精细化工品、有机中间体
- 主营：优氯净、硫酸锌、封口蜡、二萘酚、磷酸铝、戊二醛、甘露醇、水杨酸、硫酸锰、防染盐、正辛烷、牛磺酸、白僵菌、冰醋酸、铵明矾、肉桂醇、碳酸镁、肉桂醛、沸石粉、硫化钠、硫化钡、硫化钙、氯化锌、黄原胶、磺酸钙
- 主营：蛋白胨、牛骨蛋白胨、福美钠、间苯二酚双、强氯精、单乙醇胺、三乙醇胺、氯化铜、水玻璃、防辐射硫酸钡
- 主营：杜仲素、对位酯、丙烯酸酯、二氧化硫脲、二苯基硅二醇、乙基麦芽酚、饲料添加剂、油酸基硬脂酸
- 主营：全氟三丁胺、纳米勃姆石、凉味剂WS-10、二苄叉山梨醇、六氟丙烯二聚体、六氟环氧丙烷二聚体、二异戊基硫醚、新戊二醇二庚酸酯、聚六亚甲基胍磷酸盐、光引发剂2022、四氯羟铝锆GLY配位、氯化亚锡、六氟异丙醇、氟化液、薄荷醇PCA酯、氰基硼氢化钠、钒粉、泊洛沙姆188、4-氯苯硼酸、氨基磺酸钴
- 主营：甘氨酸、水苏糖、阻燃剂、磷酸铁、磷酸铝、硫酸锌、硫酸锆、硫酸锂、硫酸锶、硫酸锰、铝酸锌、1680-21-3、牛磺酸、褪黑素、丙酸铵、苏云金、碳酸镁、麝香酮、肉桂醛、王浆酸、椰油胺、赖氨酸、增塑剂、浸膏粉、乙氧基
- 主营：离子液体、咪唑、催化剂、5-二甲基吡唑、阻燃剂、正丁醇锆、四氟硼酸锂、香兰基丁醚、氟化物、全氟辛基三甲氧基硅烷、丙酮肟、双酚E型氰酸酯、叔丁基乙烯基醚、钯碳催化剂、钛硅分子筛、硫酸烟酰苯胺、丙酮缩氨基硫脲
- 主营：艾拉莫德中间体、光引发剂、苯芴醇、6-二羟基吲哚、磷钼酸、甲基丙二酸、聚二羟基吲哚、2-辛基十二醇、溴芬酸钠中间体、樟脑醌、钼酸钾、丝素蛋白、盐酸胍、β-丙氨酸甲酯盐酸盐、7-去氢胆固醇、甘氨胆酸钠盐、半叶素、胆固醇、蛋白酶K、D-荧光素钾盐、光引发剂LAP、BIS-TRIS、甲基丙烯酸氧杂环丁烷
- 主营：聚乙烯亚胺、三硫代碳酸钠40%、TS-1钛硅分子筛、三甘醇二异辛酸酯3G8、六氯环三磷腈、苯基次磷酸钠、焦磷酸哌嗪、5-甲基靛红、烷基苯磺酸酯、甲巯咪唑、吡啶硫酮锌、热敏材料、油酸甲酯、曲酸
- 主营：铜盐、锰盐、锡盐、间苯二酚磷酸酯、氧化亚镍、氧化钴、氢氧化钴、锆盐、无卤环保抑烟阻燃剂、无卤环保阻燃剂
- 主营：杀菌剂、椰子油、印染剂、磷酸铁、阻燃剂、油酸锌、润湿剂、硫酸铯、催化剂、粘合剂、乳化剂、草酸锰、硫酸锂、石英砂、绝缘油、茶皂素、防腐剂、醋酸镁、锂电池、碘化锂、培养基、蒸馏水、硬脂酸、塑化剂、草酸钾
- 主营：镭雕粉、镭雕母粒、镭雕助剂、磷酸酯类阻燃剂、阻燃剂、阻燃母粒、抗滴落剂、增韧剂、润滑剂、相容剂、成核剂、抗氧化剂、开口爽滑剂、紫外线吸收剂