Overview
Dimethylformamide (DMF) is a highly polar, aprotic solvent with broad industrial applications. It is prized for its ability to dissolve a wide range of organic and inorganic compounds, making it indispensable in chemical synthesis, pharmaceutical manufacturing, and polymer processing. DMF is produced industrially via the reaction of dimethylamine with carbon monoxide. Its unique properties, such as high boiling point and thermal stability, allow it to be used in reactions requiring elevated temperatures. However, its toxicity necessitates careful handling and storage.
Physical and Chemical Properties
DMF is a colorless, hygroscopic liquid with a faint amine-like odor. It has a density of 0.944 g/cm³ at 20°C and a boiling point of 153°C, which makes it suitable for high-temperature applications. The compound is miscible with water and most organic solvents, including alcohols, ethers, and chlorinated hydrocarbons. Its high dielectric constant (36.7 at 25°C) and dipole moment contribute to its excellent solvency power. DMF is also thermally stable, but it can decompose under extreme conditions to produce carbon monoxide and dimethylamine.
Main Applications
DMF is widely used as a solvent in the production of acrylic fibers and polyurethanes. In the pharmaceutical industry, it serves as a reaction medium for the synthesis of antibiotics, vitamins, and other active pharmaceutical ingredients (APIs). In electronics, DMF is employed in the manufacture of printed circuit boards and as a solvent for photoresists. Additionally, it is used in agrochemical formulations and as a gas absorbent for separating acetylene from hydrocarbon mixtures.
Safety and Storage
DMF poses significant health risks, including liver damage and reproductive toxicity. Exposure can occur via inhalation, skin contact, or ingestion, necessitating strict safety measures such as gloves, goggles, and respiratory protection. Storage should be in tightly sealed containers made of stainless steel or polyethylene, away from oxidizers and strong acids. Proper ventilation is critical to prevent vapor accumulation. Spills should be contained and cleaned up immediately using absorbent materials.
B2B Procurement Guide
When procuring DMF, buyers should prioritize suppliers with certifications such as ISO 9001 and REACH compliance. Key factors include purity (typically 99.5% or higher), packaging options (drums, totes, or bulk), and transportation logistics. Bulk purchases often reduce costs, but storage capacity and shelf life must be considered. Request safety data sheets (SDS) and certificates of analysis (CoA) to ensure product quality. Long-term contracts with reliable suppliers can stabilize pricing and supply chains.
Related Manufacturers
- 主营：d40溶剂、苯甲醇、白电油、二甲苯、石脑油、清洗剂、水溶肥、d60工业、稀释剂、溶剂油、正丁醇、正辛醇、桶装甲醇、单乙醇胺、辛醇、航空煤油、正辛烷、异丙醇、甲基叔丁基醚、硫酸钙晶须、正己烷、正庚烷、石油醚
- 主营：杀菌剂、硫酸铜、氟化钠、二甲苯、二月桂酸二丁基锡、乙二醇、己二酸二酰肼、二茂铁、硫酸铵、航空煤油、氯乙酸、黄血盐钠、硫酸锌、苯甲酸、叔丁醇、辛酸亚锡、多聚磷酸、多聚甲醛、乙醇、DMF、聚磷酸铵、甲醇、硝酸异辛酯、黄血盐钾
- 主营：DMF、醋酸正丙酯、正丁醇、二甲基乙酰胺、二甲基亚砜、丙二醇甲醚PM、二甲苯、偶氮二异丁腈、二氯甲烷、乙二醇丁醚、四氯乙烯、三氯乙烯、异丁醇、无水乙醇、三乙醇胺、三乙胺、环己酮、异丙醇、溶剂油、溶剂油100号120号150号
- 主营：改进剂、氯化石蜡、四氢噻吩砜、二甲基甲酰胺、表面活性剂、柴油添加剂、防冻液原料、油墨稀释剂、环氧脂肪酸甲酯、环氧甘油三酸酯
- 主营：苯乙烯、清洗剂、四氢呋喃、二甲基甲酰胺、涂料助剂、清洗粘合剂、醋酸乙烯酯、表面活性剂、甲基吡咯烷酮
- 主营：氯化铵、氯化钾、氯化钙、乙二醇、十二烷基苯磺酸钠、二甲苯、二甲基甲酰胺、二乙二醇、过硫酸铵、消泡剂、亚硝酸钠、AES、磺酸、甲酸、氢氧化钾、尿素、异丙醇、苯酚、乙酸乙酯、甲醇、乙醇、聚合硫酸铁、聚合氯化铝
- 主营：纯甘油、桶装散水、无水乙醇、乙二醇、丙二醇、二甲基甲酰胺、三乙醇胺、无色透明液体
- 主营：DMF、DMAC、碳酸丙烯酯、丙二醇、乙二醇、二氯甲烷、二甲苯、甲醇、乙醇、DOP、DBP、甘油、醋酸甲酯、醋酸乙酯、三氯乙烯、四氯乙烯、环己酮、桐油、糖蜜、DBE、PMA
- 主营：多聚甲醛、环己胺、异丙醇、正硅酸乙酯28 40、正十二烷、二甲基甲酰胺、戊二酸二甲酯、邻苯二甲酸二乙酯、二甲苯、二氯甲烷、乙二醇乙醚醋酸酯、无水乙醇、铬酸酐、亚氯酸钠、硫酸羟胺、环己烷、四氯乙烯、环己酮、环氧氯丙烷、甲醇、甲酸、乙腈、苯酚、醋酸丁酯
- 主营：二甲基甲酰胺、清洗剂、水处理、溶剂
- 主营：异丙醇、乙腈、醋酸乙烯、二甲基甲酰胺、DMF、二甲苯、二氯甲烷、乙酸乙酯、四氢呋喃、无水乙醇、苯乙烯、丙烯酸、丙烯酸甲酯、甲基丙烯酸甲酯、甲基吡咯烷酮、正庚烷、正己烷、环己烷
- 主营：乙二醇、润滑剂
- 主营：磷酸、水玻璃、次氯酸钠、二氯甲烷、戊二醛、二甲基甲酰胺、软水盐、草酸、碳酸钾、聚合氯化铝、氨水、甲酸、液碱、片碱、三氯乙烯、漂白粉、铬酸酐、乙酸乙酯、亚硝酸钠、石墨烯、硫酸铜、四氯乙烯、多聚甲醛、甲缩醛
- 主营：保险粉、苯乙烯、正庚烷、二甲苯、二氯甲烷、二甲胺、乙二醇丁醚、丙三醇、氯化钙、环己烷、冰醋酸、醋酸钠、环己酮、正己烷、环己胺、石油醚、乙醇、碳酸丙烯酯、苯甲醇、三乙醇胺、航空煤油、多聚甲醛、乙腈、吗啉
- 主营：消毒剂、酸度调节剂、工业清洗溶剂、二甲基亚砜、二甲基甲酰胺、二氯甲烷、二甲苯、可分装无色液体、工业级氢氧化铵、异丙醇、苯酚、次氯酸钠、乙醇、液碱、磷酸、甲酸、甲醇、乙酸乙酯、三乙胺、氨水、冰醋酸、过硫酸钠
- 主营：[]
- 主营：各类溶剂、桐油、松香水、二甲基亚砜、二氯甲烷、二甲基乙酰胺、三氯乙烯、乙酸乙酯、三乙醇胺、麦芽糖浆、甲酸钠
- 主营：二甲基甲酰胺、清洗剂、溶剂、水处理
- 主营：乙二醇、乙二醇丁醚、二甲基亚砜、二甲苯
- 主营：保险粉、乙酰氯、凡士林、癸二酸二辛酯、苯乙烯、杀藻铵、洗衣粉、乳胶粉、乳化剂、活性炭、乙醇胺、水杨酸、丙三醇、减水剂、环己胺、漂白粉、石蜡油、苯甲醇、四甲苯、防水剂、消泡剂、石油醚、白砂糖、硅酸钾、养护剂
- 主营：元明粉、防冻液、洗涤剂、二甲基甲酰胺、十二烷基苯磺酸、消泡剂、离子钙、三乙醇胺、碳酸氢钠、一水柠檬酸、鱼塘增氧片、酸度调节剂、硫代硫酸钠、表面活性剂、大石桥四硼酸钠
- 主营：硫酸铜、硫酸镍、片碱、丁二醇、乙二醇、苯甲酸钠、硫化钠、甲酸、液碱、铭酸酐、保险粉、亚硫酸氢钠、硼酸、苯酚
- 主营：异丙醇、醋酸丁酯、乙酰丙酮、二甲基酮、二甲基甲醇、二甲苯、咨询贝尔、丁酯化工、乙酸丁酯、醋酸异丙酯、醋酸正丁酯、六氟异丙醇、正庚烷、乙醇、丙酮肟、乙腈
- 主营：铝溶胶、硅溶胶、油酸钠、磷酸二氢铝、二氧化硫脲、二羟甲基丙酸、二甲基甲酰胺、油酸钾、十八胺、甲酸钠、硫酸氢钠、碳酸铵、尿素硝铵溶液、硝酸铵钙、碳酸亚铁、甲基硅酸、氟硅酸镁、葡萄糖酸钠、四氯乙烯、正丁醇、大苏打、硝酸铁、油酸甲酯
- 主营：白电油、无水乙醇、稀释剂、乙二醇丁醚、二丙酮醇、二甲苯、二氯甲烷、二异丁基酮、二乙二醇丁醚、二氧基二甲醚醋酸酯、二氯乙烷、石油醚、丁酯、乙酯、ECS、天那水稀释剂、洗网水开油水、碳氢清洗剂、大防白水、乙酸正丙酯、乙酸正丁酯、正丙醇、醋酸乙酯、乙酸仲丁酯、油漆稀释剂
- 主营：碘化钾、稀释剂、异辛醇、戊二醇、己二酸、二甲胺、二苯甲酮、六氟二酐、乳化剂、正辛醛、香皂香料、丁酸丁酯、六氢苯甲、红松果实、丁酸乙酯、盐酸羟胺、十一烯醛、光稳定剂、己内酰胺、乙醇酸钠、2-溴苯甲醇、2-氯丙烯腈、4-氯苯甲醇、对甲苯磺酸、染料中间体
- 主营：环乙烷、苯乙烯、丁醇nba、二甲苯、缩甲醛、石油醚、燃料油、石脑油、异辛醇、清洗剂、环己烷、溶剂d80、甲缩醛、增塑剂、稀释剂、溶剂油、黄腐酸、正丁醇、工业丁醇、工业酒精、油漆涂料、溴丁烷、辛醇、航空煤油
- 主营：甲酸、四氯乙烯、丙酸、二氯甲烷、二甲基甲酰胺、DMF、冰醋酸、辛醇、丙醇、冰乙酸、苯酚、异辛醇、正丙醇、异丙醇、甲酰胺
- 主营：太古油、防水剂、大苏打、乙二醇、二甲基乙酰胺、丙三醇、苯甲醇、己内酰胺、无碱速凝剂、表面活性剂、丙烯酸乳液、液体速凝剂、饲料添加剂、葡萄糖酸钠、硫代硫酸钠、保湿防冻剂、食用石膏粉、通用增塑剂、浓缩发酵液
- 主营：丙烯酸、丙烯酸丁酯、甲基丙烯酸、二甲基甲酰胺、甲基丙烯酸甲酯、异辛醇、正丁醇、异丁醇、三氯乙烯、四氯乙烯
- 主营：柠檬酸、山梨醇、消泡剂、乙二醇、丙二醇、二氯甲烷、二甲基硅油、二甲基甲酰胺、红山化工、三乙醇胺、山梨糖醇、无水乙醇、精炼石蜡、一乙醇胺、工业丙三醇、高纯度甘油、甲醚透明易燃、马来椰树甘油
- 主营：碳酸丙烯酯、醋酸乙酯、苯乙烯、二氯甲烷、乙醇