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Dimethyl d-malate

Updated: 2026-07-24

Overview

Dimethyl D-Malate is an organic compound with the molecular formula C6H10O5. It is a derivative of malic acid and is widely used in the pharmaceutical and chemical industries. The compound is known for its chiral properties, making it valuable in the synthesis of enantiomerically pure substances. In industrial settings, Dimethyl D-Malate serves as a key intermediate in the production of various pharmaceuticals and fine chemicals. Its versatility and reactivity make it a preferred choice for organic chemists and manufacturers.

Physical and Chemical Properties

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Dimethyl D-Malate is typically a colorless to pale yellow liquid with a density of approximately 1.2 g/cm³. It has a boiling point range of 200-220°C and is soluble in water and common organic solvents like ethanol and acetone. The compound's chiral nature allows it to be used in stereoselective synthesis, where the configuration of the molecule plays a critical role in the desired chemical reaction. Its stability under normal conditions makes it suitable for various industrial applications.

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Main Applications

Dimethyl D-Malate is primarily used in the pharmaceutical industry as an intermediate for synthesizing active pharmaceutical ingredients (APIs). Its chiral properties are particularly valuable in producing enantiomerically pure drugs, which often have higher efficacy and fewer side effects. Additionally, the compound is employed in organic synthesis as a building block for more complex molecules. It is also used in chiral resolution processes, where it helps separate enantiomers from racemic mixtures.

Safety and Storage

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When handling Dimethyl D-Malate, it is essential to follow standard safety protocols. The compound should be stored in a cool, dry place away from direct sunlight and moisture to prevent degradation. Proper ventilation is recommended to avoid inhalation of vapors. Personal protective equipment (PPE), such as gloves and safety goggles, should be worn to minimize exposure. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical attention if necessary.

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B2B Procurement Guide

When procuring Dimethyl D-Malate, it is crucial to verify the supplier's credentials and the purity of the product. Request certificates of analysis (CoA) to ensure the compound meets the required specifications for your application. Consider factors such as batch consistency, packaging, and delivery timelines when selecting a supplier. For reference, prices may vary based on quantity and supplier, so it's advisable to obtain multiple quotes before making a purchase decision.

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