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Dimethoxybenzaldehyde

Updated: 2026-07-15

Overview

Dimethoxybenzaldehyde, also known as 2,4-dimethoxybenzaldehyde, is an aromatic aldehyde derivative with two methoxy groups attached to the benzene ring. It is a key intermediate in organic synthesis, particularly in the pharmaceutical and fragrance industries. The compound is characterized by its white to pale yellow crystalline appearance and distinct aromatic properties. Dimethoxybenzaldehyde is synthesized through various chemical processes, including the formylation of dimethoxybenzene. Its structural features make it a versatile building block for more complex molecules, contributing to its widespread use in research and industrial applications.

Physical and Chemical Properties

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Dimethoxybenzaldehyde exhibits typical aldehyde properties, including reactivity with nucleophiles and the ability to undergo condensation reactions. Its molecular weight is 166.17 g/mol, and it has a melting point range of 72-75°C. The compound is soluble in common organic solvents like ethanol and ether but has limited solubility in water. The presence of two methoxy groups enhances its electron-donating effects, influencing its reactivity and stability. These groups also contribute to its distinctive aromatic odor, which is often described as sweet and slightly floral. The compound's stability under normal storage conditions makes it suitable for long-term use in various applications.

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Main Applications

Dimethoxybenzaldehyde is primarily used as an intermediate in the synthesis of pharmaceuticals, including antihypertensive and anti-inflammatory drugs. Its aromatic properties also make it a valuable component in the production of perfumes and flavoring agents. In addition to its industrial uses, the compound is employed in academic and research settings for the development of new organic compounds. Its versatility and relatively low cost make it a popular choice for chemists and manufacturers alike.

Safety and Storage

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Proper handling of dimethoxybenzaldehyde is essential to ensure safety. The compound should be stored in a cool, dry place, away from direct sunlight and moisture. It is recommended to use gloves and protective eyewear when handling to avoid skin and eye irritation. In case of accidental exposure, rinse affected areas with plenty of water and seek medical attention if necessary. The compound should be kept away from strong oxidizing agents to prevent hazardous reactions.

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B2B Procurement Guide

When procuring dimethoxybenzaldehyde, buyers should verify the CAS number (613-45-6) and purity specifications to ensure product quality. Bulk purchasing can offer cost advantages, especially for large-scale industrial applications. It is advisable to source the compound from reputable suppliers with a track record of reliability and quality assurance. Buyers should also consider logistical factors, such as shipping and storage conditions, to maintain the compound's integrity during transit.

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