Overview
Dihydroxanthatin is a naturally occurring sesquiterpene lactone isolated from plants such as Xanthium strumarium (cocklebur). It belongs to a class of compounds known for their bioactive properties, particularly in modulating inflammation and inhibiting tumor growth. Researchers value dihydroxanthatin for its potential in developing novel therapeutics, given its mechanism of action in cellular pathways. As a secondary metabolite, dihydroxanthatin is typically extracted and purified for laboratory use. Its structural features include a lactone ring, which contributes to its biological activity. The compound is primarily available to B2B buyers in the pharmaceutical and biotechnology sectors, where it serves as a reference standard or experimental agent.
Physical and Chemical Properties
Dihydroxanthatin presents as a white crystalline powder under standard conditions. Its molecular formula (C15H20O3) and weight (248.32 g/mol) reflect its moderate size and polarity. The compound is sparingly soluble in water but dissolves well in polar organic solvents like ethanol, methanol, and dimethyl sulfoxide (DMSO), making it suitable for in vitro studies. Key functional groups include an α,β-unsaturated lactone moiety, which is critical for its bioactivity. While its exact melting and boiling points are not widely documented, dihydroxanthatin is stable at room temperature when stored properly. Analytical techniques such as HPLC and NMR are commonly used to verify its purity and structural integrity.
Main Applications
The primary application of dihydroxanthatin lies in pharmaceutical research, where it is investigated for its anti-inflammatory and anticancer properties. Studies suggest it inhibits pro-inflammatory cytokines and induces apoptosis in cancer cells, making it a candidate for drug development. It is often used in preclinical trials to explore its efficacy and safety profiles. Additionally, dihydroxanthatin serves as a chemical reference in botanical and pharmacological studies. Its role in traditional medicine has spurred interest in validating its therapeutic claims through modern scientific methods. B2B procurement typically targets laboratories and institutions focused on natural product chemistry or oncology research.
Safety and Storage
Dihydroxanthatin requires careful handling due to its bioactive nature. Personal protective equipment (PPE), including gloves and lab coats, is recommended to prevent skin contact or inhalation. While toxicity data is limited, standard precautions for handling sesquiterpene lactones should be followed, as some analogs are known irritants. Storage conditions are critical to maintaining stability. The compound should be kept in airtight containers, protected from light and humidity, at temperatures below 25°C. Long-term storage may necessitate refrigeration, but repeated freeze-thaw cycles should be avoided to prevent degradation.
B2B Procurement Guide
When procuring dihydroxanthatin, buyers should prioritize suppliers who provide detailed Certificates of Analysis (COA) specifying purity (typically ≥95% for research use). Reputable vendors often offer custom synthesis or bulk quantities for large-scale studies, though lead times may vary. Pricing depends on purity and scale, with research-grade quantities commonly ranging from $50 to $200 per gram. Buyers in regulated markets should confirm compliance with regional standards (e.g., REACH, USP). For international shipments, ensure proper documentation to avoid customs delays, as some jurisdictions classify bioactive compounds under strict import controls.
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