Dihydroflavonol
Overview
Dihydroflavonol is a naturally occurring flavonoid found in various plants, including fruits, vegetables, and medicinal herbs. It belongs to the flavanonol subclass, characterized by a saturated C2-C3 bond and a hydroxyl group at the C3 position. This compound is valued for its bioactive properties, particularly its antioxidant and anti-inflammatory effects, which have sparked interest in pharmaceutical and nutraceutical applications. In industrial contexts, dihydroflavonol is often extracted from plant sources like citrus fruits or synthesized for standardized formulations. Its stability and compatibility with other ingredients make it a versatile additive in functional foods, dietary supplements, and skincare products.
Physical and Chemical Properties
Dihydroflavonol appears as a pale yellow to white crystalline powder with a molecular weight of 240.25 g/mol. It has a melting point of 170-175°C and is soluble in organic solvents like ethanol and DMSO, though only slightly soluble in water. Its density is approximately 1.3 g/cm³, and it exhibits stability under dry, cool storage conditions. Key chemical properties include its ability to scavenge free radicals due to the phenolic hydroxyl groups in its structure. This reactivity underpins its antioxidant capacity, which is harnessed in formulations aimed at reducing oxidative stress. The compound’s low volatility and moderate thermal stability make it suitable for processing in food and pharmaceutical manufacturing.
Main Applications
In the pharmaceutical industry, dihydroflavonol is studied for its potential neuroprotective and cardioprotective effects, with research exploring its role in mitigating neurodegenerative diseases and cardiovascular conditions. It is also used in nutraceuticals to enhance antioxidant intake, often blended with vitamins or other flavonoids. The food industry incorporates dihydroflavonol as a natural preservative or functional additive in beverages, health bars, and fortified products. In cosmetics, it is valued for its anti-aging properties, appearing in serums and creams aimed at reducing UV-induced skin damage. Industrial buyers should note that application-specific purity grades (e.g., >95% for pharmaceuticals) may influence procurement decisions.
Safety and Storage
Dihydroflavonol is generally considered safe for consumption in regulated amounts, with no significant toxicity reported at typical dosages. However, occupational handling requires precautions: use gloves and goggles to avoid skin/eye irritation, and ensure adequate ventilation to prevent inhalation of fine particles. Storage recommendations include keeping the compound in airtight containers, protected from light and moisture, at temperatures below 25°C. Prolonged exposure to heat or humidity may degrade its efficacy. For large-scale storage, desiccants and climate-controlled environments are advisable to maintain stability over time.
B2B Procurement Guide
When sourcing dihydroflavonol, prioritize suppliers with transparent quality control documentation, such as Certificates of Analysis (CoA) detailing purity, heavy metal content, and residual solvents. Bulk buyers should negotiate pricing tiers, as orders exceeding 100 kg often qualify for discounts (approximately 10-20%). Consider regional regulations: for example, pharmaceutical-grade dihydroflavonol may require additional compliance with USP or EP standards. Logistics planning should account for the compound’s stability—avoid shipping during extreme temperatures. Establish long-term contracts with reliable suppliers to ensure consistent quality and mitigate supply chain disruptions.
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