Overview
Dihydrocarbamazepine, also known as 10,11-Dihydrocarbamazepine, is a derivative of carbamazepine, a well-known anticonvulsant and mood-stabilizing drug. It is primarily used as an intermediate in pharmaceutical research and development. This compound is of interest due to its structural similarity to carbamazepine, which allows it to be used in studies aimed at understanding drug metabolism and developing new therapeutic agents. Its role in research makes it a valuable chemical for pharmaceutical companies and academic institutions.
Physical and Chemical Properties
Dihydrocarbamazepine is a white to off-white crystalline powder with a molecular weight of 238.28 g/mol. It has a melting point range of approximately 190-194°C and is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound is stable under recommended storage conditions and is non-hygroscopic, making it relatively easy to handle in laboratory settings. Its stability and solubility profile make it suitable for various research applications, including synthesis and formulation studies.
Main Applications
The primary application of dihydrocarbamazepine is as a pharmaceutical intermediate in the synthesis of carbamazepine and its analogs. It is also used in research to study drug metabolism and the development of new anticonvulsant and mood-stabilizing medications. In addition to its role in drug development, dihydrocarbamazepine is sometimes used in academic research to explore the pharmacological properties of carbamazepine derivatives. Its versatility makes it a valuable tool for scientists working in medicinal chemistry and pharmacology.
Safety and Storage
Dihydrocarbamazepine should be handled with care to avoid inhalation, ingestion, or skin contact. Personal protective equipment, such as gloves and lab coats, should be worn when working with this compound. Storage conditions should include a cool, dry place away from light and moisture to maintain stability. Proper labeling and secure containers are essential to prevent accidental exposure. In case of exposure, seek medical attention and refer to the material safety data sheet (MSDS) for specific guidance.
B2B Procurement Guide
When procuring dihydrocarbamazepine, buyers should prioritize suppliers who provide a Certificate of Analysis (CoA) to verify purity and quality. It is also important to ensure that the supplier complies with relevant regulatory requirements for research chemicals. Buyers should consider the intended use of the compound and select the appropriate grade (e.g., research-grade or pharmaceutical-grade). Pricing can vary significantly based on purity and quantity, so obtaining multiple quotes is recommended. Additionally, buyers should verify the supplier's reputation and track record for reliability and customer service.
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